ACVR2A

Gene Symbol ACVR2A
Entrez Gene 92
Alt Symbol ACTRII, ACVR2
Species Human
Gene Type protein-coding
Description activin A receptor, type IIA
Other Description activin receptor type-2A
Swissprots P27037 D3DP85 Q6NWV2 Q92474 Q53TH4 B4DWQ2 B2RAB8
Accessions AAX93050 CCF77014 EAX11561 EAX11562 P27037 AA125825 AK301629 BAG63114 AK314124 BAG36815 AW162986 BC067416 BC067417 AAH67417 BC067418 AAH67418 BC069707 AAH69707 BG616903 BM503220 BU676046 BX645435 D31770 BAA06548 DA531622 DN918410 M93415 AAA35504 T07746 W03601 X62381 CAA44245 X63128 CAA44839 XM_005263843 XP_005263900 NM_001278579 NP_001265508 NM_001278580 NP_001265509 NM_001616 NP_001607
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells

Human Activin Receptor Type IIA full length protein - ab114448 from Abcam

Category Protein
Source Wheat germ
Species Human
ab114448 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Human Activin Receptor Type IIA protein fragment - ab114449 from Abcam

Category Protein
Source Wheat germ
Species Human
ab114449 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Human Activin Receptor Type IIA protein fragment - ab152023 from Abcam

Category Protein
Source HEK 293 cells
Species Human

Human Activin Receptor Type IIA protein fragment - ab125548 from Abcam

Category Protein
Source Baculovirus infected sf9 cells
Species Human
SDS-PAGE analysis of ab125548.

ACVR2 / ACVR2A Antibody Blocking Peptide - LS-E3753 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

ACVR2 / ACVR2A Antibody Blocking Peptide - LS-E8693 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Activin RIIA Protein - H00000092-Q01 from Novus Biologicals

Category Protein
Prices $529.00
Sizes 25 µg
Source Wheat Germ
Species Human

Activin RIIA Recombinant Protein - H00000092-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Activin RIIA Peptide - P2244 from Novus Biologicals

Category Peptide
Species Human

ACVR2A-Antibody-N-term-Blocking-Peptide - BP7103a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human Activin RIIA Fc Chimera - 340-R2-100 from R&D Systems

Category Protein
Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived

Recombinant Human Activin RIIA Fc Chimera, CF - 340-R2-100/CF from R&D Systems

Category Protein
Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived

Recombinant Human Activin RIIA Fc Chimera (CHO), CF - 340-RC2-100 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived

Human ACVR2A Fc tag protein - orb82851 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 100 μg, 200 μg
Source Human
Species Human
SDS-PAGE analysis of human ACVR2A Fc tag protein

Human ACVR2A His tag protein - orb84010 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 100 μg, 200 μg
Source Human
Species Human
SDS-PAGE analysis of human ACVR2A His tag protein

Human Activin RIIA protein - orb180164 from Biorbyt

Category Protein
Prices $213.00, $408.00, $850.00, $1,088.00
Sizes 10 μg, 50 μg, 500 μg, 1 mg
Source HEK293
Species Human

Human ACVR2A Protein - abx065140 from Abbexa

Category Protein
Source E.coli
Species Human

Activin receptor type 2A (ACVR2A) - H00000092-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Activin receptor type 2A (ACVR2A) - H00000092-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

Activin receptor type 2A (ACVR2A) - H00000092-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Activin receptor type 2A (ACVR2A) - H00000092-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Activin receptor type 2A (ACVR2A) - P5491 from Acris Antibodies

Category Protein
Prices $840.00
Sizes 5 µg
Species Human

Activin A Receptor Type II A (ACVR2A), Human - 20-8360 from ARP American Research Products

Category Protein
Prices $507.00
Sizes 50 µg
Source E.coli
Species Human

Activin Receptor Type-2A, Activin RIIA, Human, Recombinant - 19-C561 from ARP American Research Products

Category Protein
Prices $109.00
Sizes 10 µg
Source HEK293
Species Human

ACVR2A Recombinant Protein - 96-008 from ProSci

Category Protein
Prices $425.00
Sizes 200 µg
Source HEK293 cells
Species Human
The purity of rh ACVR2A / ACVR2 Fc Chimera was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.
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