Gene Symbol | Itgb4 |
---|---|
Entrez Gene | 192897 |
Alt Symbol | AA407042, C230078O20, CD104 |
Species | Mouse |
Gene Type | protein-coding |
Description | integrin beta 4 |
Other Description | integrin beta-4 |
Swissprots | A2A866 Q8R3J1 Q91W15 A2A865 A2A863 Q6PCS0 |
Accessions | A2A863 EDL34539 EDL34540 EDL34541 AA407046 AK048888 AK140269 BAE24307 AK142648 AK144111 BAE25705 AK145317 BAE26363 AK147424 BC006632 AAH06632 BC025194 AAH25194 BC038607 BC059192 AAH59192 BC080751 AAH80751 BE863493 BF139425 BY019731 CD563279 CK796475 L04678 X58254 XM_006532572 XP_006532635 XM_006532573 XP_006532636 XM_006532574 XP_006532637 XM_011248818 XP_011247120 XM_011248819 XP_011247121 XM_011248820 XP_011247122 NM_001005608 NP_001005608 NM_133663 NP_598424 |
Function | Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Cell junction, hemidesmosome {ECO:0000250}. Note=Colocalizes with DST at the leading edge of migrating keratinocytes. {ECO:0000250}. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy |
Integrin beta-4 (ITGB4), Mouse, ELISA Kit - CSB-EL011887MO from ARP American Research Products
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Mouse Integrin beta-4(ITGB4) ELISA kit - CSB-EL011887MO from Cusabio
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integrin, beta 4, ELISA Kit - MBS919775 from MyBioSource
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Mouse Integrin beta-4 (ITGB4) ELISA Kit - EKC37122 from Biomatik
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Mouse Itgb4 ELISA Kit - E056916 from Biobool
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