| Gene Symbol |
GAS8
|
| Entrez Gene |
2622
|
| Alt Symbol |
GAS11
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
growth arrest-specific 8
|
| Other Description |
GAS-11|GAS-8|growth arrest specific 11|growth arrest-specific 11|growth arrest-specific protein 11|growth arrest-specific protein 8
|
| Swissprots |
B7Z4U1 Q2M234 G3V1L5 O95995 B2RCT1
|
| Accessions |
AAC69518 EAW66658 EAW66659 EAW66660 EAW66661 O95995 AF050079 AAC69519 AK127378 AK293958 BAH11635 AK294050 BAH11659 AK297857 BAH12677 AK303505 BAH13976 AK304731 BAH14246 AK315261 BAG37678 BC036781 BC104785 AAI04786 BC112121 AAI12122 BX647947 CR749499 CAH18322 DA504655 DC370728 DC371501 XM_005256304 XP_005256361 XM_005256309 XP_005256366 XM_006721175 XP_006721238 XM_011522990 XP_011521292 XM_011522991 XP_011521293 XM_011522992 XP_011521294 NM_001286205 NP_001273134 NM_001286208 NP_001273137 NM_001286209 NP_001273138 NM_001481 NP_001472 NR_023348
|
| Function |
Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cytoskeleton, flagellum basal body {ECO:0000250}. Golgi apparatus {ECO:0000250}. Note=Associates with microtubules. Localized to the cytoplasm of round spermatids, the tails of elongating spermatids, and mature spermatid tail bundles protruding into the lumen, and in the flagellum of epididymal spermatozoa. {ECO:0000250}.
|
| Tissue Specificity |
Expressed in the heart, skeletal muscle, pancreas and liver. Weakly or not expressed in brain, placenta, lung and kidney. {ECO:0000269|PubMed:9790751}.
|