EPHX2

Gene Symbol EPHX2
Entrez Gene 2053
Alt Symbol CEH, SEH
Species Human
Gene Type protein-coding
Description epoxide hydrolase 2, cytoplasmic
Other Description bifunctional epoxide hydrolase 2|epoxide hydratase|epoxide hydrolase 2, cytosolic|epoxide hydrolase, soluble
Swissprots J3KPH7 Q9HBJ2 Q9HBJ1 P34913 G3V134 Q16764 B3KUA0 B3KTU8 B2Z3B1
Accessions ACD11487 CAA65751 EAW63547 EAW63548 EAW63549 EAW63550 EAW63551 P34913 AF233334 AAG14966 AF233335 AAG14967 AF233336 AAG14968 AK094393 AK096089 BAG53210 AK096770 BAG53362 AK294065 BAG57410 AK303904 BAG64834 AK308041 AK310507 BC007708 AAH07708 BC011628 AAH11628 BC013874 AAH13874 BQ272362 BT006885 AAP35531 BX103698 CA397329 DC331720 DQ892749 ABM83675 DQ895995 ABM86963 L05779 AAA02756 NM_001256482 NP_001243411 NM_001256483 NP_001243412 NM_001256484 NP_001243413 NM_001979 NP_001970
Function Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo- 9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro- 9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy- octadec-9Z-enoic acid, 12-phosphonooxy-octadec-9E-enoic acid, and p-nitrophenyl phospate. {ECO:0000269|PubMed:12574508, ECO:0000269|PubMed:12574510}.
Subcellular Location Cytoplasm. Peroxisome.
Top Pathways Peroxisome, Arachidonic acid metabolism

sEH CRISPR/Cas9 KO Plasmid (h) - sc-402095 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

sEH HDR Plasmid (h) - sc-402095-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EPHX2 Double Nickase Plasmid (h) - sc-402095-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

sEH Double Nickase Plasmid (h2) - sc-402095-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EPHX2 CRISPR Activation Plasmid (h) - sc-402095-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

sEH CRISPR Activation Plasmid (h2) - sc-402095-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EPHX2 Lentiviral Activation Particles (h) - sc-402095-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

sEH Lentiviral Activation Particles (h2) - sc-402095-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

sEH siRNA (h) - sc-44090 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

sEH shRNA Plasmid (h) - sc-44090-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

sEH shRNA (h) Lentiviral Particles - sc-44090-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EPHX2 RNAi - H00002053-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU007681 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7922 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7922 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

EPHX2 siRNA (Human) - CRH1430 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EPHX2 - MBS8223727 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human EPHX2 siRNA - orb261932 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EPHX2 shRNA Plasmid (Human) - CHH1430 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EPHX2 miRNA 3'UTR clone - MiUTR3H-00752 from Creative biogene

Species Reactivities Human
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