Gabarapl2

Gene Symbol Gabarapl2
Entrez Gene 93739
Alt Symbol 0610012F20Rik, 2900019O08Rik, AI173605, GATE-16, Gef2
Species Mouse
Gene Type protein-coding
Description gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
Other Description GABA(A) receptor-associated protein like 2|GABA(A) receptor-associated protein-like 2|gamma-aminobutyric acid (GABA-A) receptor-associated protein-like 2|gamma-aminobutyric acid receptor-associated protein-like 2|ganglioside expression factor 2|golgi-associated ATPase enhancer of 16 kDa
Swissprots P60521
Accessions EDL11519 P60521 AF190644 AAK16238 AI845404 AK002596 BAB22217 AK013563 AK049819 BAC33933 AK134873 AK184306 BC026798 AAH26798 BC081436 AAH81436 NM_026693 NP_080969
Function Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. {ECO:0000250}.
Subcellular Location Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, autophagosome {ECO:0000250}.
Tissue Specificity Ubiquitous. A high level expression is seen in brain, thymus, lung, heart, liver and kidney. {ECO:0000269|PubMed:11414770}.
Top Pathways GABAergic synapse, Regulation of autophagy

GABARAP-2 CRISPR/Cas9 KO Plasmid (m) - sc-430041 from Santa Cruz Biotechnology

Category CRISPR
Species Reactivities Mouse

GABARAP-2 HDR Plasmid (m) - sc-430041-HDR from Santa Cruz Biotechnology

Species Reactivities Mouse

GABARAP-2 Double Nickase Plasmid (m) - sc-430041-NIC from Santa Cruz Biotechnology

Species Reactivities Mouse

GABARAP-2 Double Nickase Plasmid (m2) - sc-430041-NIC-2 from Santa Cruz Biotechnology

Species Reactivities Mouse

GABARAP-2 CRISPR Activation Plasmid (m) - sc-430041-ACT from Santa Cruz Biotechnology

Category CRISPR
Species Reactivities Mouse

GABARAP-2 CRISPR Activation Plasmid (m2) - sc-430041-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Species Reactivities Mouse

GABARAP-2 Lentiviral Activation Particles (m) - sc-430041-LAC from Santa Cruz Biotechnology

Species Reactivities Mouse

GABARAP-2 Lentiviral Activation Particles (m2) - sc-430041-LAC-2 from Santa Cruz Biotechnology

Species Reactivities Mouse

GABARAPL2 siRNA (m) - sc-41959 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

GABARAPL2 shRNA Plasmid (m) - sc-41959-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

GABARAPL2 shRNA (m) Lentiviral Particles - sc-41959-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU171241 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN31655 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31655 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GABARAPL2 siRNA (Mouse) - CRN0256 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

GABARAPL2 - MBS8205272 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse GABARAPL2 (NM_026693.5) - SHH298373 from Creative biogene

Category siRNA
Species Reactivities Mouse

GABARAPL2 shRNA Plasmid (Mouse) - CHN0256 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
Search more