| Gene Symbol |
COL5A2
|
| Entrez Gene |
1290
|
| Alt Symbol |
EDSC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
collagen, type V, alpha 2
|
| Other Description |
AB collagen|collagen alpha-2(V) chain|collagen, fetal membrane, A polypeptide|type V preprocollagen alpha 2 chain
|
| Swissprots |
Q6LDJ5 Q13908 Q96QB0 P78440 P05997 Q53WR4 Q96QB3 Q86XF6 Q59GR4 Q7KZ55
|
| Accessions |
AAA51858 AAC41699 AAL13165 AAL13166 AAY24185 CDM55399 CDM55580 EAX10906 EAX10907 EAX10908 P05997 AB209045 BAD92282 AK297936 BAG60252 AK300146 BAG61932 AL552427 BC015705 BC043613 AAH43613 BC086874 AAH86874 J04478 AAA51859 M10956 AAA52007 M11135 AAA51857 M11718 AAA52058 M31365 X04758 CAA28454 Y14690 CAA75002 XM_011510573 XP_011508875 NM_000393 NP_000384
|
| Function |
Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue- specific matrices (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}.
|
| Top Pathways |
Focal adhesion, ECM-receptor interaction, Amoebiasis, Protein digestion and absorption, PI3K-Akt signaling pathway
|
![Western Blot: Collagen V alpha 2 Overexpression Lysate (Adult Normal) [NBL1-09355] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Collagen V alpha 2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1829_Collagen%2520V%2520alpha%25202%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09355-img0002.jpg)