Hmgcl

Gene Symbol	Hmgcl
Entrez Gene	15356
Alt Symbol	AW476067, HL
Species	Mouse
Gene Type	protein-coding
Description	3-hydroxy-3-methylglutaryl-Coenzyme A lyase
Other Description	3-hydroxy-3-methylglutarate-CoA lyase|HMG-CoA lyase|hydroxymethylglutaryl-CoA lyase, mitochondrial
Swissprots	Q8QZS6 P38060
Accessions	AAB03107 EDL29963 P38060 AK077842 AK132035 BAE20956 AK144768 BAE26056 AK145251 BAE26328 AK154033 BAE32329 AK182431 AK210917 AK217644 BB852743 BC025440 AAH25440 BX631310 S65036 AAB27965 XM_006538563 XP_006538626 XM_006538564 XP_006538627 NM_008254 NP_032280
Function	Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta- hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism (By similarity). {ECO:0000250}.
Subcellular Location	Mitochondrion matrix {ECO:0000269|PubMed:7527399}. Peroxisome {ECO:0000269|PubMed:7527399}. Note=Unprocessed form is peroxisomal.
Top Pathways	Peroxisome, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse Hmgcl ORF Clone(NM_008254.2) - CDCL166249 from Creative Biomart Species Mouse Accession NM_008254.2

Mouse Hmgcl ORF Clone(NM_008254.2) - CDCL166250 from Creative Biomart Species Mouse Accession NM_008254.2

Mouse HMGCL ORF clone(NM_008254.2) - CDCR006058 from Creative Biomart Species Mouse Accession NM_008254.2

Mouse HMGCL Gene ORF cDNA clone in cloning vector - MG52804-G from Sino Biological Species Mouse

Mouse HMGCL Gene ORF cDNA clone expression plasmid, N-HA tag - MG52804-NY from Sino Biological Species Mouse

Mouse HMGCL Gene ORF cDNA clone expression plasmid, C-Flag tag - MG52804-CF from Sino Biological Species Mouse

Mouse HMGCL Gene ORF cDNA clone expression plasmid - MG52804-UT from Sino Biological Species Mouse

Mouse HMGCL Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - MG52804-ANG from Sino Biological Species Mouse

Mouse HMGCL Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - MG52804-ACG from Sino Biological Species Mouse

Mouse HMGCL Gene ORF cDNA clone expression plasmid, N-Flag tag - MG52804-NF from Sino Biological Species Mouse

Mouse HMGCL Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - MG52804-ACR from Sino Biological Species Mouse

Mouse HMGCL Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - MG52804-ANR from Sino Biological Species Mouse

Mouse HMGCL Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-tagged - MG52804-CH from Sino Biological Species Mouse Accession NM_008254.2

Mouse HMGCL Gene ORF cDNA clone expression plasmid, N-Myc tag - MG52804-NM from Sino Biological Species Mouse

Mouse HMGCL Gene ORF cDNA clone expression plasmid, C-Myc tag - MG52804-CM from Sino Biological Species Mouse

Mouse HMGCL Gene ORF cDNA clone expression plasmid, C-HA tag - MG52804-CY from Sino Biological Species Mouse

Mouse HMGCL Gene ORF cDNA clone expression plasmid, N-His tag - MG52804-NH from Sino Biological Species Mouse

Mouse HMGCL ORF clone(NM_008254.2) - CDCR006058 from Creative biogene Species Mouse

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