HMOX1

Gene Symbol	HMOX1
Entrez Gene	3162
Alt Symbol	HMOX1D, HO-1, HSP32, bK286B10
Species	Human
Gene Type	protein-coding
Description	heme oxygenase 1
Other Description	heat shock protein, 32-kD|heme oxygenase (decycling) 1
Swissprots	P09601
Accessions	AAR23262 CAA32886 EAW60059 P09601 AF051791 AK313120 BAG35941 BC001491 AAH01491 BP288767 BT019785 AAV38588 CA306357 CR456505 CAG30391 CR541945 CAG46743 CR541968 CAG46766 CU013103 CAK54534 CU013391 CAK54833 DQ892310 ABM83236 DQ895510 ABM86436 GU187011 ACZ72606 GU187012 ACZ72607 JF323038 ADZ76424 M23041 AAA50403 M23042 X06985 CAA30045 NM_002133 NP_002124
Function	Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
Subcellular Location	Microsome {ECO:0000269|PubMed:22419571}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:22419571}; Peripheral membrane protein {ECO:0000269|PubMed:22419571}; Cytoplasmic side {ECO:0000269|PubMed:22419571}.
Tissue Specificity	Expressed at higher levels in renal cancer tissue than in normal tissue (at protein level). {ECO:0000269|PubMed:20855888}.
Top Pathways	Mineral absorption, MicroRNAs in cancer, Porphyrin and chlorophyll metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HMOX1 - MBS1274792 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC001491

Human HMOX1 ORF Clone(NM_002133.2) - CDCL166271 from Creative Biomart Species Human Accession NM_002133.2

Human HMOX1 Gene cDNA clone plasmid - HG16608-U from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 Gene cDNA Clone (full-length ORF Clone), expression ready, N-GFPSpark-tagged - HG16608-ANG from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 natural ORF mammalian expression plasmid, C-Flag tag - HG16608-CF from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 natural ORF mammalian expression plasmid, C-His tag - HG16608-CH from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 natural ORF mammalian expression plasmid, C-Myc tag - HG16608-CM from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 natural ORF mammalian expression plasmid, C-HA tag - HG16608-CY from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 natural ORF mammalian expression plasmid, C-GFPSpark tag - HG16608-ACG from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 natural ORF mammalian expression plasmid, N-Flag tag - HG16608-NF from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 natural ORF mammalian expression plasmid, N-His tag - HG16608-NH from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-tagged - HG16608-NM from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 natural ORF mammalian expression plasmid, N-HA tag - HG16608-NY from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 natural ORF mammalian expression plasmid - HG16608-UT from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 natural ORF mammalian expression plasmid, C-OFPSpark tag - HG16608-ACR from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 natural ORF mammalian expression plasmid, N-OFPSpark tag - HG16608-ANR from Sino Biological Species Human Accession NM_002133.2

Human HMOX1 ORF Clone (BC001491) - CDCS410638 from Creative biogene Species Human Accession P09601

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