Vkorc1

Gene Symbol Vkorc1
Entrez Gene 27973
Alt Symbol D7Wsu86e
Species Mouse
Gene Type protein-coding
Description vitamin K epoxide reductase complex, subunit 1
Other Description phylloquinone epoxide reductase|vitamin K epoxide reductase complex subunit 1|vitamin K1 2,3-epoxide reductase subunit 1|vitamin K1 epoxide reductase (warfarin-sensitive)
Swissprots Q9CRC0
Accessions EDL17600 EDL17601 Q9CRC0 AK002742 BAB22320 AK003237 BAB22661 AK008509 BAB25708 AK008578 BAB25757 AK013996 BAB29106 BC031732 AAH31732 CD774913 NM_178600 NP_848715
Function Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development. {ECO:0000269|PubMed:15879509, ECO:0000269|PubMed:19492146}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Detected in liver. {ECO:0000269|PubMed:19492146}.
Top Pathways Ubiquinone and other terpenoid-quinone biosynthesis

VKORC1 CRISPR/Cas9 KO Plasmid (m) - sc-424300 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

VKORC1 HDR Plasmid (m) - sc-424300-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

VKORC1 Double Nickase Plasmid (m) - sc-424300-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

VKORC1 Double Nickase Plasmid (m2) - sc-424300-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

VKORC1 CRISPR Activation Plasmid (m) - sc-424300-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

VKORC1 CRISPR Activation Plasmid (m2) - sc-424300-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

VKORC1 Lentiviral Activation Particles (m) - sc-424300-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

VKORC1 Lentiviral Activation Particles (m2) - sc-424300-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

VKORC1 siRNA (m) - sc-155112 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

VKORC1 shRNA Plasmid (m) - sc-155112-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

VKORC1 shRNA (m) Lentiviral Particles - sc-155112-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU018001 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN44123 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND44123 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

VKORC1 siRNA (Mouse) - CRM4961 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

VKORC1 - MBS8211858 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse VKORC1 (NM_178600.2) - SHH442828 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Vkorc1(NM_178600.2) - SHL126252 from Creative biogene

Category siRNA
Species Reactivities Mouse

VKORC1 shRNA Plasmid (Mouse) - CHM4961 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

VKORC1 miRNA 3'UTR clone - MiUTR1M-12688 from Creative biogene

Species Reactivities Mouse
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