| Gene Symbol |
CLDN5
|
| Entrez Gene |
7122
|
| Alt Symbol |
AWAL, BEC1, CPETRL1, TMVCF
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
claudin 5
|
| Other Description |
TMDVCF|claudin-5|transmembrane protein deleted in VCFS|transmembrane protein deleted in velocardiofacial syndrome
|
| Swissprots |
B3KS11 O00501 Q8WUW3 Q53XW2
|
| Accessions |
EAX03034 EAX03035 O00501 AF000959 AAC51364 AK092561 BAG52573 AK124019 AK222466 BAD96186 BC002404 AAH02404 BC019290 AAH19290 BC032363 AAH32363 BT007254 AAP35918 BU688528 CB993999 CR456420 CAG30306 CU012981 CAK54412 CU013269 CAK54711 DB023636 NM_001130861 NP_001124333 NM_003277 NP_003268
|
| Function |
Plays a major role in tight junction-specific obliteration of the intercellular space. {ECO:0000250}.
|
| Subcellular Location |
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C
|
![Western Blot: Claudin 5 Overexpression Lysate (Adult Normal) [NBL1-09247] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Claudin 5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11733_Claudin%25205%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-09247-img0002.jpg)