| Gene Symbol |
S1pr2
|
| Entrez Gene |
14739
|
| Alt Symbol |
1100001A16Rik, Edg5, Gpcr13, H218, LPb2, S1P2
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
sphingosine-1-phosphate receptor 2
|
| Other Description |
G-protein coupled receptor 13|S1P receptor 2|S1P receptor Edg-5|endothelial differentiation G-protein coupled receptor 5|endothelial differentiation, sphingolipid G-protein-coupled receptor, 5|lysophospholipid receptor B2|sphingosine 1-phosphate receptor 2|sphingosine 1-phosphate receptor Edg-5|sphingosine-1-phosphate receptor S1P(2)
|
| Swissprots |
Q9R236 P52592 Q8C3Q7
|
| Accessions |
AAD16976 EDL25146 P52592 AK003144 AK085114 BAC39368 AK134275 BAE22078 AK151062 BAE30079 AK153398 BAE31960 AK159605 BAE35224 AK170436 BAE41795 AK196049 BC096760 AAH96760 BY095108 L20334 AAA16846 XM_006510019 XP_006510082 NM_010333 NP_034463
|
| Function |
Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Most abundant in heart and lung; low, but clearly observed in kidney, liver and thymus; much lower but detectable in brain, testis, stomach and intestine. Not significantly detected in any of the sections of embryonic day (E) 14-18, except in embryonic brain. {ECO:0000269|PubMed:9931453}.
|
| Top Pathways |
Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction
|