Gene Symbol |
Tnfrsf13c
|
Entrez Gene |
72049
|
Alt Symbol |
2010006P15Rik, BAFF-R, Baffr, Bcmd, Bcmd-1, Bcmd1, Lvis22
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
tumor necrosis factor receptor superfamily, member 13c
|
Other Description |
B-cell maturation defect 1|B-cell-activating factor receptor|BAFF receptor|BLyS receptor 3|b cell-activating factor receptor|tumor necrosis factor receptor superfamily member 13C
|
Swissprots |
Q9D8D0
|
Accessions |
Q9D8D0 AF350257 AAL83914 AF373847 AAK91827 AK008142 BAB25490 AK156387 BAE33695 AK172406 BAE42991 BC104126 AAI04127 BC104127 AAI04128 DQ294928 ABC24673 DQ294929 ABC24674 XM_006521428 XP_006521491 NM_028075 NP_082351
|
Function |
B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. {ECO:0000269|PubMed:11747827}.
|
Subcellular Location |
Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}.
|
Tissue Specificity |
Highly expressed in spleen and testis; detected at lower levels in lung and thymus.
|
Top Pathways |
Cytokine-cytokine receptor interaction, Primary immunodeficiency, Intestinal immune network for IgA production, HTLV-I infection
|