| Gene Symbol |
Eef1a1
|
| Entrez Gene |
13627
|
| Alt Symbol |
-
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
eukaryotic translation elongation factor 1 alpha 1
|
| Other Description |
EF-1-alpha-1|EF-Tu|eEF1A-1|elongation factor 1 A-1|elongation factor 1-alpha 1|elongation factor Tu|eukaryotic elongation factor 1 A-1
|
| Swissprots |
Q61511 Q8BVS8 Q6ZWN2 Q8BMB8 P10126 Q99KU5
|
| Accessions |
EDL26400 P10126 AK003188 AK011771 AK012341 AK032914 BAC28085 AK050635 AK076696 BAC36446 AK081725 BAC38311 AK083361 BAC38884 AK088041 AK133725 BAE21802 AK135448 BAE22537 AK137223 BAE23278 AK141243 AK150798 BAE29861 AK151479 BAE30434 AK151773 BAE30679 AK152810 BAE31515 AK152993 AK153387 BAE31951 AK153402 BAE31962 AK153851 AK162049 BAE36697 AK162313 BAE36848 AK162440 BAE36918 AK163799 BAE37497 AK164113 BAE37633 AK164671 BAE37870 AK165938 BAE38472 AK166021 BAE38526 AK166033 BAE38534 AK166058 BAE38549 AK166089 BAE38564 AK166615 BAE38895 AK166807 BAE39035 AK167843 BAE39863 AK167873 AK168424 AK168467 AK183068 AK185520 AK186242 AK187140 AK188001 AK188863 AK190580 AK190942 AK191230 AK192548 AK192994 AK194234 AK194451 AK194927 AK194947 AK195943 AK196468 AK196726 AK197236 AK197803 AK198561 AK199391 AK200818 AK204290 AK204373 AK204572 AK206186 AK206299 AK208452 AK209036 AK210348 AK210662 AK210766 AK212450 AK213386 AK213893 AK213920 AK217934 AK218081 BC003969 BC004005 AAH04005 BC004067 AAH04067 BC005660 AAH05660 BC018223 AAH18223 BC018485 AAH18485 BC040689 BC050124 BC068258 BC083069 AAH83069 BC092053 AAH92053 BC092276 AAH92276 BC092292 BC095965 AAH95965 BC099609 AAH99609 BC108391 AAI08392 BY227095 EF437368 M22432 AAA50406 X03688 CAA27324 X13661 CAA31957 NM_010106 NP_034236
|
| Function |
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:19856081}. Nucleus {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Note=Colocalizes with DLC1 at actin-rich regions in the cell periphery. Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens (By similarity). {ECO:0000250}.
|
| Top Pathways |
RNA transport, Legionellosis
|