COP1

Gene Symbol COP1
Entrez Gene 817857
Alt Symbol ARABIDOPSIS THALIANA CONSTITUTIVE PHOTOMORPHOGENIC 1, ATCOP1, CONSTITUTIVE PHOTOMORPHOGENIC 1, DEETIOLATED MUTANT 340, DET340, EMB168, EMBRYO DEFECTIVE 168, FUS1, FUSCA 1, T21L14.11, T21L14_11
Species Arabidopsis thaliana
Gene Type protein-coding
Description E3 ubiquitin-protein ligase COP1
Other Description -
Swissprots Q1JPL6 O48770 O23974 O23975 P43254
Accessions AAB91983 AEC08766 P43254 BT025337 ABF57293 NM_128855 NP_180854
Function E3 ubiquitin-protein ligase that acts as a repressor of photomorphogenesis and as an activator of etiolation in darkness. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Represses photomorphogenesis in darkness by mediating ubiquitination and subsequent proteasomal degradation of light-induced transcription factors such as HY5, HYH and LAF1. Down-regulates MYB21, probably via ubiquitination process. Light stimuli abrogate the repression of photomorphogenesis, possibly due to its localization to the cytoplasm. Could play a role in switching between skotomorphogenetic and photomorphogenetic pathways. {ECO:0000269|PubMed:11967090, ECO:0000269|PubMed:12023303}.
Subcellular Location Nucleus. Cytoplasm. Note=Localizes to the nucleus in darkness but is gradually relocated to the cytoplasm upon illumination. Localizes to subnuclear foci (speckle) and in dispersed nuclear localization in the dark.
Top Pathways Ubiquitin mediated proteolysis, Circadian rhythm - plant

Recombinant Arabidopsis thaliana E3 ubiquitin-protein ligase COP1(COP1) ,partial - CSB-YP337358DOA CSB-EP337358DOA CSB-BP337358DOA CSB-MP337358DOA from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Arabidopsis thaliana

E3 ubiquitin-protein ligase COP1 (COP1), partial, Recombinant Protein - MBS1035956 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Arabidopsis thaliana
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