CES1

Gene Symbol CES1
Entrez Gene 1066
Alt Symbol ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1
Species Human
Gene Type protein-coding
Description carboxylesterase 1
Other Description acyl coenzyme A:cholesterol acyltransferase|acyl-coenzyme A:cholesterol acyltransferase|brain carboxylesterase hBr1|carboxylesterase 1 (monocyte/macrophage serine esterase 1)|carboxylesterase 2 (liver)|cholesteryl ester hydrolase|cocaine carboxylesterase|egasyn|human monocyte/macrophage serine esterase 1|liver carboxylesterase 1|methylumbelliferyl-acetate deacetylase 1|monocyte/macrophage serine esterase|retinyl ester hydrolase|serine esterase 1|triacylglycerol hydrolase
Swissprots Q16788 Q16737 Q13657 Q00015 Q9ULY2 Q9UDG8 Q96EE8 Q9UK77 Q9UC52 P82127 Q86UK2 A8K3K8 A8K844 Q549X7 A6NIM1 E9PAU8 Q14062 P23141 Q549X8
Accessions BAA04650 BAC87750 BAC87751 BAE48735 BAE48737 BAE48738 BAE48739 BAE48740 CAA65527 EAW82838 EAW82839 EAW82840 P23141 AB025026 BAA84995 AB119995 BAC87748 AB119996 BAC87749 AF177775 AAD53175 AK290623 BAF83312 AK292209 BAF84898 AK301651 BAH13531 AU139632 AY268104 AAP20868 BC009706 BC012418 AAH12418 BC110338 AAI10339 CB137639 DQ891472 ABM82398 DQ894656 ABM85582 L07764 AAA16036 L07765 AAA35711 M55509 AAA35650 M65261 AAA83932 M73499 AAA35649 S73751 AAC60631 X52973 CAA37147 XM_005255774 XP_005255831 XM_005276867 XP_005276924 XM_011522816 XP_011521118 XM_011546995 XP_011545297 NM_001025194 NP_001020365 NM_001025195 NP_001020366 NM_001266 NP_001257
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate. {ECO:0000269|PubMed:7980644, ECO:0000269|PubMed:9169443}.
Subcellular Location Endoplasmic reticulum lumen {ECO:0000269|PubMed:10562416}.
Tissue Specificity Expressed predominantly in liver with lower levels in heart and lung. {ECO:0000269|PubMed:10562416}.
Top Pathways Drug metabolism - other enzymes

Rat Carboxylesterase 1 / CES1 ELISA Kit (Sandwich ELISA) - LS-F7737 from LifeSpan Bioscience

Category ELISA Kit
Prices $780.00
Sizes 1 plate
Sensitivity 14.1 pg/ml
Range 31.25-2000 pg/ml

Acetyl-CoA acetyltransferase, mitochondrial (ACAT1), Human, ELISA Kit - CSB-EL001134HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Carboxylesterase 1, Human, ELISA Kit - E01C0060 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Catenin Alpha 1 (CTNNa1), Human, ELISA Kit - SEC201Hu from ARP American Research Products

Category ELISA Kit
Prices $720.00
Sizes 96 t
Sensitivity 0.054ng/mL
Range 0.156-10ng/mL

Cocaine esterase (CES2), Human, ELISA Kit - E01C1624 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Epoxide hydrolase 2 (EPHX2), Human, ELISA Kit - CSB-EL007735HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 5.86 pg/ml
Range 23.44 pg/ml-1500 pg/ml

Carboxylesterase 1, ELISA Kit - MBS079397 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxylesterase 1, ELISA Kit - MBS060231 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxylesterase 1, ELISA Kit - MBS091762 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxylesterase 1, ELISA Kit - MBS720254 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxylesterase 1, ELISA Kit - MBS082053 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxylesterase 1, ELISA Kit - MBS100270 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxylesterase 1, ELISA Kit - MBS087767 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxylesterase 1, ELISA Kit - MBS083443 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carboxylesterase 1 (CES1), ELISA Kit - MBS2025059 from MyBioSource

Category ELISA Kit
Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.055ng/mL.
Range 0.156-10ng/mL

carboxylesterase 1 (monocyte/macrophage serine esterase 1) , ELISA Kit - MBS9337115 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Carboxylesterase 1 (CES1) - SEC374Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Carboxylesterase 1 (CES1) - SEC374Ra from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 14.1pg/mL.
Range 31.25-2000pg/mL The standard curve concentrations used for the ELISA’s were 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL

ELISA Kit for Carboxylesterase 1 (CES1) - SEC374Hu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.055ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Catenin Alpha 1 (CTNNa1) - SEC201Hu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Carboxylesterase 1 (CES1) ELISA Kit - EKU08515 from Biomatik

Category ELISA Kit
Prices $735.00, $3,234.00, $5,880.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 0.057 ng/mL
Range 0.156-10 ng/mL

Human Carboxylesterase 1 ELISA Kit - abx156849 from Abbexa

Category ELISA Kit
Range 0.156 ng/ml - 10 ng/ml

Custom Human Carboxylesterase 1 ELISA - ELH-CES1 from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human Carboxylesterase 1 / CES1 ELISA Kit (Sandwich ELISA) - LS-F25366 from LifeSpan Bioscience

Category ELISA Kit
Prices $780.00
Sizes 1 plate
Sensitivity 0.057 ng/ml
Range 31.25-2000 pg/ml

Human Carboxylesterase 1 ELISA Kit - orb319915 from Biorbyt

Category ELISA Kit
Prices $1,148.00, $1,981.00, $4,284.00
Sizes 96 assays, 192 assays, 480 assays
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