EPX

Gene Symbol EPX
Entrez Gene 8288
Alt Symbol EPO, EPP, EPX-PEN
Species Human
Gene Type protein-coding
Description eosinophil peroxidase
Other Description -
Swissprots Q4TVP3 P11678
Accessions AAA58458 AAY43126 EAW94479 EAW94480 P11678 AJ705406 AL597635 BC111602 AAI11603 BM147889 X14346 CAA32530 NM_000502 NP_000493
Function Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis. {ECO:0000269|PubMed:12540536, ECO:0000269|PubMed:18694936}.
Subcellular Location Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils.
Top Pathways Asthma

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