ABCB1

Gene Symbol ABCB1
Entrez Gene 5243
Alt Symbol ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family B (MDR/TAP), member 1
Other Description P-glycoprotein 1|colchicin sensitivity|doxorubicin resistance|multidrug resistance protein 1
Swissprots A8K294 P08183 Q12755 Q14812 B5AK60
Accessions AAA59576 AAA88047 AAA88048 AAB70218 AAM49149 AAR99172 AAW82430 ACH96452 AEC13104 AEC13105 AEC13106 AEC13107 AEC13108 AEC13109 AEC13110 AEC13111 AEC13112 AEC13113 AEC13114 AEC13115 AEC13116 AEC13117 AEC13118 AEC13119 AEC13120 AEC13121 AEC13122 AEC13123 AEC13124 AEC13125 AEC13126 AEC13127 AEC13128 AEC13129 AEC13130 AEC13131 AEC13132 AEC13133 AEC13134 AEC13135 AEC13136 AEC13137 AEC13138 AEC13139 AEC13140 AEC13141 AEC13142 AEC13143 AEC13144 AEC13145 AEC13146 AEC13147 AEC13148 AEC13149 AEC13150 AEC13151 AEC13152 AEC13153 AEC13154 AEC13155 AEC13156 AEC13157 AEC13158 AEC13159 AEC13160 AEC13161 AEC13162 AEC13163 AEC13164 AEC13165 AEC13166 AEC13167 AEC13168 AEC13169 AEC13170 AEC13171 AEC13172 AEC13173 AEC13174 AEC13175 AEC13176 AEC13177 AEC13178 AEC13179 AEC13180 AEC13181 AEC13182 AEC13183 AEC13184 AEC13185 AEC13186 AEC13187 AEC13188 AEC13189 AEC13190 AEC13191 AEC13192 AEC13193 AEC13194 AEC13195 AEC13196 AEC13197 AEC13198 AEC13199 AEC13200 AEC13201 AEC13202 AEC13203 AEC13204 AEC13205 AEC13206 AEC13207 AEC13208 AEC13209 AEC13210 AEC13211 AEC13212 AEC13213 AEC13214 AEC13215 AEC13216 AEC13217 AEC13218 AEC13219 AEC13220 AEC13221 AEC13222 AEC13223 AEC13224 AEC13225 AEC13226 AEC13227 AEC13228 AEC13229 AEC13230 AEC13231 AEC13232 AEC13233 AEC13234 AEC13235 AEC13236 AEC13237 AEC13238 AEC13239 AEC13240 AEC13241 AEC13242 AEC13243 AEC13244 AEC13245 AEC13246 AEC13247 AEC13248 AEC13249 AEC13250 AEC13251 AEC13252 AEC13253 AEC13254 AEC13255 AEC13256 AEC13257 AEC13258 AEC13259 AEC13260 AEC13261 AEC13262 AEC13263 AEC13264 AEC13265 AEC13266 AEC13267 AEC13268 AEC13269 AEC13270 AEC13271 AEC13272 AEC13273 AEC13274 AEC13275 AEC13276 AEC13277 AEC13278 AEC13279 AEC13280 AEC13281 AEC13282 AEC13283 AEC13284 AEC13285 AEC13286 AEC13287 AEC13288 AEC13289 AEC13290 AEC13291 AEC13292 AEC13293 AEC13295 AEC13296 AEC13297 AEC13298 AEC13299 AEC13300 CAA41558 EAL24173 EAW76940 EAW76941 EAW76942 EAW76943 P08183 AA776371 AB208970 BAD92207 AF016535 AAB69423 AF345623 AF345624 AF345625 AF345626 AK290159 BAF82848 AK308467 AM393352 CAL38230 AY425005 AAR91621 AY425006 AAR91622 AY425007 AAR83914 AY452673 BC130424 AAI30425 BQ720763 BQ882401 BX509020 CB164676 EU852583 ACF94687 EU854148 ACF94688 M14758 AAA59575 NM_000927 NP_000918
Function Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
Tissue Specificity Expressed in liver, kidney, small intestine and brain.
Top Pathways ABC transporters, Bile secretion, MicroRNAs in cancer

Rat ABCB1 / MDR1 / P Glycoprotein ELISA Kit (Sandwich ELISA) - LS-F12019 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.312
Range 0.312-20 ng/ml

Human ABCB1 / MDR1 / P Glycoprotein ELISA Kit (Sandwich ELISA) - LS-F12020 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.156
Range 0.312-20 ng/ml

Mouse ABCB1 / MDR1 / P Glycoprotein ELISA Kit (Sandwich ELISA) - LS-F12021 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.156
Range 0.312-20 ng/ml

Multidrug resistance protein 1, ABCB1, Human, ELISA Kit - E8039h from ARP American Research Products

Category ELISA Kit
Prices $660.00
Sizes 96 t
Range 0.156-10 ng/mL

Permeability Glycoprotein, P-GP, Human, ELISA Kit - E-EL-H0915 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 0.188
Range 0.313-20ng/mL

Permeability Glycoprotein (Pgp), Human, ELISA Kit - SEB690Hu from ARP American Research Products

Category ELISA Kit
Prices $685.00
Sizes 96 t
Sensitivity 0.114ng/mL
Range 0.312-20ng/mL

Permeability glycoprotein, P-gp/ABCB1, Human, ELISA Kit - CSB-E11709h from ARP American Research Products

Category ELISA Kit
Prices $565.00, $835.00, $837.00, $839.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 0.78ng/ml
Range 3.12 ng/ml-200 ng/ml

Permeability Glycoprotein, P-GP, Rabbit, ELISA Kit - E-EL-RB0409 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Permeability Glycoprotein, P-GP, Chicken, ELISA Kit - E-EL-Ch0977 from ARP American Research Products

Category ELISA Kit
Prices $504.00
Sizes 96 t

Permeability Glycoprotein, P-GP, Porcine, ELISA Kit - E-EL-P1217 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Permeability Glycoprotein, P-GP, Sheep, ELISA Kit - E-EL-S0785 from ARP American Research Products

Category ELISA Kit
Prices $648.00
Sizes 96 t

Permeability Glycoprotein, P-GP, Guinea Pig, ELISA Kit - E-EL-GP0388 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Permeability Glycoprotein, P-GP, Monkey, ELISA Kit - E-EL-MK2218 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Human P-gp ELISA Kit - HP0661 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Human P-gp ELISA Kit - HP0008 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Anserine P-GP ELISA Kit - AP0008 from NeoScientific

Category ELISA Kit
Prices $300.00, $480.00
Sizes 100 µl, 200 µl

Anserine P-gp ELISA Kit - AP0661 from NeoScientific

Category ELISA Kit
Prices $495.00
Sizes 96 t

Human P-GP(Permeability Glycoprotein) ELISA Kit - E-EL-H0915 from Elabscience

Category ELISA Kit
Sensitivity 0.19 ng/mL
Range 0.31—20 ng/mL

Human P-GP (Permeability Glycoprotein) CLIA Kit - E-CL-H0625 from Elabscience

Category CLIA Kit
Sensitivity 37.50 pg/mL
Range Average Recovery (%)

ATP-binding cassette, sub-family B (MDR/TAP) , member 1, ELISA Kit - MBS701812 from MyBioSource

Category ELISA Kit
Prices $250.00, $575.00, $835.00, $3,040.00, $5,755.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human ABCB1 is typically less than 0.78 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 3.12 ng/ml -200 ng/ml.

ELISA Kit for Permeability Glycoprotein (Pgp) - SEB690Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.122ng/mL.
Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Permeability Glycoprotein (Pgp) - SEB690Mu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 0.059ng/mL.
Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

MDR1 Shift Assay - ECM905 from EMD Millipore

MDR1 Efflux Assay - ECM910 from EMD Millipore

Human permeability glycoprotein,P-gp/ABCB1 ELISA Kit - CSB-E11709h from Cusabio

Category ELISA Kit
Sensitivity 0.78 ng/ml
Range 3.12 ng/ml-200 ng/ml
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