| Gene Symbol |
CHRM1
|
| Entrez Gene |
1128
|
| Alt Symbol |
HM1, M1, M1R
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cholinergic receptor, muscarinic 1
|
| Other Description |
acetylcholine receptor, muscarinic 1|muscarinic acetylcholine receptor M1
|
| Swissprots |
Q96RH1 P11229
|
| Accessions |
CAA33334 CAA36291 CAA68560 EAW74124 EAW74125 EAW74126 P11229 AF385587 AAK68112 AF498915 AAM18938 AJ006520 CAA07081 AK312374 BAG35292 BC007740 AAH07740 BC022984 AAH22984 BT007166 AAP35830 DQ890725 ABM81651 DQ892720 ABM83646 DQ895969 ABM86895 XM_011544742 XP_011543044 NM_000738 NP_000729
|
| Function |
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
|
| Top Pathways |
Calcium signaling pathway, PI3K-Akt signaling pathway, cAMP signaling pathway, Regulation of actin cytoskeleton, Neuroactive ligand-receptor interaction
|
![Western Blot: Muscarinic Acetylcholine Receptor 1 Overexpression Lysate (Adult Normal) [NBL1-09173] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Muscarinic Acetylcholine Receptor 1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4619_Muscarinic%2520Acetylcholine%2520Receptor%25201%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09173-img0002.jpg)