CDC25A

Gene Symbol CDC25A
Entrez Gene 993
Alt Symbol CDC25A2
Species Human
Gene Type protein-coding
Description cell division cycle 25A
Other Description CDC25 isoform A1-CAG|CDC25A2-CAG isoform|M-phase inducer phosphatase 1|dual specificity phosphatase CDC25A
Swissprots P30304 Q8IZH5 Q9H2F2 Q96IL3
Accessions AAM77917 AAY85387 EAW64849 EAW64850 EAW64851 EAW64852 P30304 AF277722 AAG41884 AI917350 AK290554 BAF83243 AY137580 AAN11305 BC007401 AAH07401 BC018642 AAH18642 BQ065803 BX392016 DQ890753 ABM81679 DQ892919 ABM83845 DQ896168 ABM87167 EU812118 ACI43572 FJ866789 ACZ05628 M81933 AAA58415 XM_006713434 XP_006713497 XM_006713435 XP_006713498 XM_006713436 XP_006713499 XM_011534316 XP_011532618 NM_001789 NP_001780 NM_201567 NP_963861
Function Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.
Top Pathways Cell cycle, Progesterone-mediated oocyte maturation, MicroRNAs in cancer

cdc25A Antibody - 3652 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from asynchronous (lane 1) or synchronized (lanes 2-4) NIH/3T3 cells, using Phospho-cdc25A (Thr506) Antibody #3654 (upper) or cdc25A Antibody (lower). Cells were synchronized by mitotic shake-off and replated for the indicated times.

Phospho-cdc25A (Thr506) Antibody - 3654 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

Cdc25A (DCS-120) - sc-56264 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc25A (DCS-120): sc-56264. Western blot analysis of Cdc25A expression in HeLa (A) and K-562 (B) whole cell lysates.

Cdc25A (M-191) - sc-7157 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Cdc25A (M-191): sc-7157. Western blot analysis of Cdc25A expression in WEHI-231 whole cell lysate.

Cdc25A (DCS-124) - sc-65505 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc25A (DCS-124): sc-65505. Western blot analysis of Cdc25A expression in non-transfected: sc-110760 (A) and human Cdc25A transfected: sc-158364 (B) 293 whole cell lysates.

Cdc25A (DCS-122) - sc-65503 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc25A (DCS-122): sc-65503. Immunoperoxidase staining of formalin fixed, paraffin-embedded human hippocampus tissue showing cytoplasmic staining of neuronal cells and glial cells and neuropil staining.

Cdc25A (F-6) - sc-7389 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc25A siRNA (h): sc-29254. Western blot analysis of Cdc25A expression in non-transfected control (A) and Cdc25A siRNA transfected (B) HeLa cells. Blot probed with Cdc25A (F-6): sc-7389. GAPDH (V-18): sc-20357 used as specificity and loading control.

Cdc25A (N-15) - sc-6947 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Cdc25A (N-15): sc-6947. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lower stomach tissue showing cytoplasmic staining of glandular cells.

Cdc25A (SPM233) - sc-56265 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc25A (SPM233): sc-56265. Western blot analysis of Cdc25A expression in K-562 (A), SK-N-MC (B), BJAB (C) and HeLa (D) whole cell lysates.

Cdc25A (DCS 121) - sc-56263 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Cdc25A (144) - sc-97 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Cdc25A (144): sc-97. Western blot analysis of Cdc25A expression in K-562 whole cell lysate.

Cdc25A (3H2016) - sc-70823 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc25A (3H2016): sc-70823. Western blot analysis of Cdc25A expression in HeLa (A) and K-562 (B) whole cell lysates.

Cdc25A (5H51) - sc-70824 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc25A (5H51): sc-70824. Western blot analysis of Cdc25A expression in non-transfected: sc-110760 (A) and human Cdc25A transfected: sc-158364 (B) 293 whole cell lysates.

p-Cdc25A (Ser 76) - sc-101655 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-Cdc25A (Ser 76): sc-101655. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing cytoplasmic localization.

p-Cdc25A (Ser 79) - sc-130590 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-Cdc25A (Ser 79): sc-130590. Western blot analysis of Cdc25A phosphorylation in untreated (A) and lambda protein phosphatase treated (B) HeLa whole cell lysates.

Anti-Cdc25A (phospho S124) antibody - ab135545 from Abcam

Prices $359.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Cdc25A (phospho S124) antibody (ab135545) at 1/100 dilution + Mouse liver tissue lysate at 12.5 µg

Anti-Cdc25A (phospho S124) antibody - ab182666 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cdc25A (phospho S124) antibody (ab182666) at 1/500 dilutionLane 1 : UV treated 293 cell extract with immunizing peptideLane 2 : UV treated 293 cell extract

Anti-Cdc25A (phospho S124) antibody - ab63391 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cdc25A (phospho S124) antibody (ab63391) at 1/500 dilutionLane 1 : Extracts from 293 cells treated with UV (15mins)Lane 2 : Extracts from 293 cells treated with UV (15mins) plus peptide

Anti-Cdc25A (phospho S124) antibody [EPR8888] - ab156574 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8888
All lanes : Anti-Cdc25A (phospho S124) antibody [EPR8888] (ab156574) at 1/1000 dilutionLane 1 : HeLa cell lysate, untreatedLane 2 : HeLa cell lysate treated with Alkaline PhosphataseLysates/proteins at 10 µg per lane.

Anti-Cdc25A (phospho S17) antibody - ab18321 from Abcam

Prices $380.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Cdc25A (phospho S178) antibody - ab79252 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Left panel: immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using 1/50 ab79252. Right panel: same, after pre-incubation with the immunizing peptide.

Anti-Cdc25A (phospho S278) antibody - ab59977 from Abcam

Prices $313.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Cdc25A (phospho S278) antibody (ab59977) at 1/100 dilution + Mouse heart tissue lysate

Anti-Cdc25A (phospho S75) antibody - ab47279 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cdc25A (phospho S75) antibody (ab47279) at 1/500 dilutionLane 1 : Extracts from A2780 cells. UV + no blocking peptide. Lane 2 : Extracts from A2780 cells. Without UV + without blocking peptide.

Anti-Cdc25A (phospho S75) antibody - ab196004 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cdc25A (phospho S75) antibody (ab196004) at 1/500 dilutionLane 1 : UV treated A2780 whole cell lysate with antigen specific peptideLane 2 : UV treated A2780 whole cell lysateLysates/proteins at 12.5 µg per lane.

Anti-Cdc25A (phospho S76) antibody - ab75743 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab75743, at a 1/50 dilution, staining Cdc25A in paraffin embedded human breast carcinoma tissue by Immunohistochemistry, in the absence (left image) or presence (right image) of the immunizing phospho peptide.
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