| Gene Symbol |
UNC5D
|
| Entrez Gene |
137970
|
| Alt Symbol |
PRO34692, Unc5h4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
unc-5 homolog D (C. elegans)
|
| Other Description |
netrin receptor UNC5D|netrin receptor Unc5h4|protein unc-5 homolog 4|protein unc-5 homolog D|unc-5 homolog 4
|
| Swissprots |
Q8WYP7 Q6UXZ4
|
| Accessions |
EAW63381 EAW63382 EAW63383 Q6UXZ4 AB055056 BAB83663 AB073394 AK092313 AK122610 BAG53621 AK122615 AY358147 AAQ88514 BC156113 AAI56114 BC156908 AAI56909 BY798317 XM_006716288 XP_006716351 XM_011544398 XP_011542700 XM_011544399 XP_011542701 XM_011544400 XP_011542702 XM_011544401 XP_011542703 XM_011544402 XP_011542704 XM_011544403 XP_011542705 XM_011544404 XP_011542706 XM_011544405 XP_011542707 NM_080872 NP_543148
|
| Function |
Receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|
| Top Pathways |
Axon guidance
|