FKBP5

Gene Symbol FKBP5
Entrez Gene 2289
Alt Symbol AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10
Species Human
Gene Type protein-coding
Description FK506 binding protein 5
Other Description 51 kDa FK506-binding protein|51 kDa FKBP|54 kDa progesterone receptor-associated immunophilin|FF1 antigen|FKBP-51|HSP90-binding immunophilin|PPIase FKBP5|T-cell FK506-binding protein|androgen-regulated protein 6|peptidyl-prolyl cis-trans isomerase FKBP5|peptidylprolyl cis-trans isomerase|rotamase
Swissprots Q13451 F5H7R1 Q59EB8 Q5TGM6
Accessions EAX03841 EAX03842 Q13451 AB209893 BAD93130 AF194172 AAL54872 AK222807 BAD96527 AK302704 BAH13784 AK303356 BAH13948 AK312422 BAG35332 AL122066 AM393744 CAL38619 AW182642 BC042605 AAH42605 BC111050 AAI11051 BX647390 DB066174 U42031 AAA86245 U71321 AAC51189 X97300 NM_001145775 NP_001139247 NM_001145776 NP_001139248 NM_001145777 NP_001139249 NM_004117 NP_004108
Function Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded.
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Widely expressed, enriched in testis compared to other tissues.
Top Pathways Estrogen signaling pathway

FKBP5 Antibody - 8245 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa and SH-SY5Y cells using FKBP5 Antibody.

FKBP5 (D5G2) Rabbit mAb - 12210 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D5G2
Western blot analysis of extracts from HT-1080 and HeLa cells using FKBP5 (D5G2) Rabbit mAb.

FKBP51 (D-4) - sc-271547 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FKBP51 (D-4): sc-271547. Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate tissue showing nuclear staining of subset of glandular cells.

FKBP51 (F-13) - sc-11514 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FKBP51 (F-13): sc-11514. Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing nuclear and cytoplasmic staining of glandular cells.

FKBP51 (H-100) - sc-13983 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FKBP51 (H-100): sc-13983. Immunoperoxidase staining of formalin fixed, paraffin-embedded human appendix tissue showing nuclear staining of glandular and lymphoid cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

FKBP51 (F-14) - sc-11518 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FKBP51 (F-14): sc-11518. Western blot analysis of FKBP51 expression in mouse thymus extract.

Anti-FKBP51 antibody [3E9] - ab118050 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E9
All lanes : Anti-FKBP51 antibody [3E9] (ab118050) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY FKBP51 cDNALysates/proteins at 5 µg per lane.

Anti-FKBP51 antibody [EPR6617] - ab126715 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6617
All lanes : Anti-FKBP51 antibody [EPR6617] (ab126715) at 1/1000 dilutionLane 1 : Human testis cell lysateLane 2 : Jurkat cell lysateLane 3 : Caco-2 cell lysateLane 4 : HeLa cell lysate

Anti-FKBP51 antibody [EPR6617] (Alexa Fluor® 488) - ab198978 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6617
Overlay histogram showing HeLa cells stained with ab198978 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab198978, 1/500 dilution) for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) Alexa Fluor® 488 (ab199091) used at the same concentration and conditions as the primary antibody. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HeLa cells fixed with 4% formaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-FKBP51 antibody [EPR6617] (Alexa Fluor® 647) - ab198979 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6617
ab198979 staining FKBP51 in HeLa cells. The cells were fixed with 4% formaldehyde (10min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab198979 at 1/100 dilution (shown in red) and ab7291 (Mouse monoclonal [DM1A] to alpha Tubulin) at 1µg/ml. This was followed by an incubation at room temperature for 1h with ab150117, Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) preadsorbed, at 1µg/ml (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-FKBP5 / FKBP51 Antibody (aa394-407) - LS-C15185 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FKBP5 / FKBP51 Antibody (aa2-457) - LS-C36345 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-FKBP5 / FKBP51 Antibody - LS-C129035 from LifeSpan Bioscience

Prices $365.00
Sizes 25 µg
Host Mouse
Clonality Monoclonal

Anti-FKBP5 / FKBP51 Antibody (clone Hi51B, Atto 390) - LS-C227359 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Hi51B

Anti-FKBP5 / FKBP51 Antibody (clone Hi51B, Atto 488) - LS-C227360 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Hi51B

Anti-FKBP5 / FKBP51 Antibody (clone Hi51B, Atto 565) - LS-C227361 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Hi51B

Anti-FKBP5 / FKBP51 Antibody (clone Hi51B, Atto 594) - LS-C227362 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Hi51B

Anti-FKBP5 / FKBP51 Antibody (aa208-257) - LS-C186699 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Thymus Tumor. FKBP5 antibody dilution 1.0 ug/ml.

Anti-FKBP5 / FKBP51 Antibody (clone Hi51B, Atto 633) - LS-C227363 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Hi51B

Anti-FKBP5 / FKBP51 Antibody (clone Hi51B, Atto 655) - LS-C227364 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Hi51B

Anti-FKBP5 / FKBP51 Antibody (clone Hi51B, Atto 680) - LS-C227365 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Hi51B

Anti-FKBP5 / FKBP51 Antibody (clone Hi51B, Atto 700) - LS-C227366 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Hi51B

Anti-FKBP5 / FKBP51 Antibody (clone Hi51B, APC) - LS-C227367 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Hi51B

Anti-FKBP5 / FKBP51 Antibody (clone Hi51B, AP) - LS-C227368 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Hi51B

Anti-FKBP5 / FKBP51 Antibody (clone Hi51B, Biotin) - LS-C227369 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Hi51B
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