ADAMTS4

Gene Symbol	ADAMTS4
Entrez Gene	9507
Alt Symbol	ADAMTS-2, ADAMTS-4, ADMP-1
Species	Human
Gene Type	protein-coding
Description	ADAM metallopeptidase with thrombospondin type 1 motif, 4
Other Description	A disintegrin and metalloproteinase with thrombospondin motifs 4|ADAM-TS 4|ADAM-TS4|a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4|aggrecanase-1
Swissprots	Q5VTW2 Q2HYD0 Q6P4Q8 Q6UWA8 O75173 Q9UN83
Accessions	AAL02262 EAW52627 O75173 AB014588 BAA31663 AF148213 AAD41494 AK291573 BAF84262 AL603427 AY358886 AAQ89245 BC030812 BC063293 AAH63293 DA098917 DQ364570 ABC88384 XM_006711635 XP_006711698 NM_005099 NP_005090
Function	Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Tissue Specificity	Expressed in brain, lung and heart. Expressed at very low level in placenta and skeletal muscles. Isoform 2 is detected in osteoarthritic synovium. {ECO:0000269|PubMed:23897278}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ADAMTS4 ELISA Kit (Sandwich ELISA) - LS-F7250 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.134 ng/ml Range 0.313-20 ng/ml

Rat ADAMTS4 ELISA Kit (Sandwich ELISA) - LS-F9386 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.313-20 ng/ml

Human ADAMTS4 ELISA Kit (Sandwich ELISA) - LS-F10525 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 20 pg/ml Range 0.313-20 ng/ml

Rat ADAMTS4 ELISA Kit (Sandwich ELISA) - LS-F10900 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 0.313-20 ng/ml

ADAMTS4 Colorimetric Assay Kit - KA1498 from Novus Biologicals Category Assay Kit Prices $1,499.00 Sizes 1 kit

ADAMTS4 Colorimetric Assay Kit - KA1497 from Novus Biologicals Category Assay Kit Prices $1,149.00 Sizes 1 kit

Human ADAMTS4 ELISA Kit - abx150553 from Abbexa Category ELISA Kit Sensitivity 0.128 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human ADAMTS4 ELISA Kit - abx054910 from Abbexa Category ELISA Kit Sensitivity 0.8 pg/ml Range 4 pg/ml - 300 pg/ml

A Disintegrin And Metalloproteinase With Thrombospondin 4 (ADAMTS4), Human, ELISA Kit - SEK204Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 26.3pg/mL Range 62.5-4,000pg/mL

A disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAMTS3), Human, ELISA Kit - CSB-EL001310HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4), Human, ELISA Kit - E01A0940 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/ml

A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAMTS4, Human, ELISA Kit - E1804h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 1.56-100 IU/mL

ADAM metallopeptidase with thrombospondin type 1 motif4, ADAMTS4, Human, ELISA Kit - CSB-E11848h from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

ADAM with Thrombospondin Type 1 Motif 4, ADAMTS4, Human, ELISA Kit - E-EL-H0266 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

ADAM with Thrombospondin Type 1 Motif4, ADAMTS4, Rabbit, ELISA Kit - E-EL-RB1004 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

ADAM with Thrombospondin Type 1 Motif4, ADAMTS4, Chicken, ELISA Kit - E-EL-Ch1675 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

ADAM with Thrombospondin Type 1 Motif4, ADAMTS4, Porcine, ELISA Kit - E-EL-P0907 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

ADAM with Thrombospondin Type 1 Motif4, ADAMTS4, Monkey, ELISA Kit - E-EL-MK1126 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

ADAMTS4 (Human) IP-WB Antibody Pair - H00009507-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

ADAMTS4 (Human) IP-WB Antibody Pair - H00009507-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Custom Human ADAMTS-4 ELISA - ELH-ADAMTS4 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human ADAMTS4 ELISA Kit - HD0023 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine ADAMTS4 ELISA Kit - AD0023 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

A disintegrin and metalloproteinase with thrombospondin motifs 4, ELISA Kit - MBS282450 from MyBioSource Category ELISA Kit Prices $425.00, $720.00, $3,160.00, $6,055.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

A disintegrin and metalloproteinase with thrombospondin motifs 4, ELISA Kit - MBS177535 from MyBioSource Category ELISA Kit Prices $425.00 Sizes 1x96 wells Sensitivity <20pg/ml Range 625pg/ml-40,000pg/ml

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