MAP2K2

Gene Symbol MAP2K2
Entrez Gene 5605
Alt Symbol CFC4, MAPKK2, MEK2, MKK2, PRKMK2
Species Human
Gene Type protein-coding
Description mitogen-activated protein kinase kinase 2
Other Description ERK activator kinase 2|MAP kinase kinase 2|MAPK/ERK kinase 2|dual specificity mitogen-activated protein kinase kinase 2|mitogen-activated protein kinase kinase 2, p45
Swissprots P36507
Accessions EAW69262 EAW69263 EAW69264 EAW69265 P36507 AA312322 AK093125 BAG52659 AK126446 AK129586 BAC85187 BC000471 AAH00471 BC018645 AAH18645 BX538081 CAD98005 DQ893601 ABM84527 DQ895060 ABM85986 L11285 XM_006722799 XP_006722862 XM_011528133 XP_011526435 NM_030662 NP_109587
Function Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity). {ECO:0000250}.
Top Pathways Rap1 signaling pathway, Choline metabolism in cancer, cGMP-PKG signaling pathway, Prolactin signaling pathway, Sphingolipid signaling pathway

SignalSilence ® MEK2 siRNA II - 6532 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (3 nmol)
Species Reactivities Human
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-) or SignalSilence ® MEK2 siRNA II (+), using MEK2 (13E3) Rabbit mAb #9147 and α-Tubulin (11H10) Rabbit mAb #2125. MEK2 (13E3) Rabbit mAb confirms silencing of MEK2 expression, while the α-Tubulin (11H10) Rabbit mAb is used to control for loading and specificity of MEK2 siRNA.

SignalSilence ® MEK2 siRNA I - 6431 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (50-100 transfections)
Species Reactivities Human
Western blot analysis of extracts from HeLa cells transfected with 100 nM control siRNA #6201 (lane 1), MEK1 siRNA (lane 2), MEK2 siRNA (lane 3) or MEK1 and MEK2 siRNA (Lane 4), using MEK2 Antibody #9125 (upper) or MEK1 Antibody #9124 (lower) in combination with GCK Antibody #3782. The MEK2 Antibody confirms silencing of MEK2 expression, MEK1 Antibody demonstrates MEK2 siRNA has no effect on its homologue MEK1, and GCK Antibody is used to control for loading and specificity of MEK2 siRNA.

MEK-2 CRISPR/Cas9 KO Plasmid (h) - sc-402732 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEK-2 HDR Plasmid (h) - sc-402732-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEK-2 Double Nickase Plasmid (h) - sc-402732-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEK-2 Double Nickase Plasmid (h2) - sc-402732-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEK-2 CRISPR Activation Plasmid (h) - sc-402732-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEK-2 CRISPR Activation Plasmid (h2) - sc-402732-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEK-2 Lentiviral Activation Particles (h) - sc-402732-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEK-2 Lentiviral Activation Particles (h2) - sc-402732-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MEK-2 siRNA (h) - sc-35905 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MEK-2 shRNA Plasmid (h) - sc-35905-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MEK-2 shRNA (h) Lentiviral Particles - sc-35905-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MEK2 RNAi - H00005605-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® siRNA - SIHK1099 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1100 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK1101 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN1591 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1591 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02314 from Sigma-Aldrich

Category miRNA

MAP2K2 siRNA (Human) - CRH3775 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MAP2K2 (NM_030662.3) - SHH337539 from Creative biogene

Category siRNA
Species Reactivities Human

MAP2K2 shRNA Plasmid (Human) - CHH3775 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MAP2K2 miRNA 3'UTR clone - MiUTR3H-04005 from Creative biogene

Species Reactivities Human
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