PSMA6

Gene Symbol PSMA6
Entrez Gene 5687
Alt Symbol IOTA, PROS27, p27K
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) subunit, alpha type, 6
Other Description 27 kDa prosomal protein|PROS-27|macropain iota chain|macropain subunit iota|multicatalytic endopeptidase complex iota chain|prosomal P27K protein|proteasome iota chain|proteasome subunit alpha type-6|proteasome subunit iota
Swissprots B4DQR4 P60900 B4DXJ9 Q6IB60 P34062 B2R7J9
Accessions AAG61139 EAW65876 EAW65877 P60900 AA090836 AK298920 BAG61026 AK302008 BAG63411 AK313011 BAG35846 AK316223 BAH14594 BC002979 AAH02979 BC017882 AAH17882 BC022354 AAH22354 BC023659 AAH23659 BC070137 AAH70137 BG701535 BQ009843 BU198521 BU657545 CR456944 CAG33225 D28434 BAA05800 DQ892346 ABM83272 DQ895551 ABM86477 HY028439 X59417 CAA42052 X61972 CAA43964 NM_001282232 NP_001269161 NM_001282233 NP_001269162 NM_001282234 NP_001269163 NM_002791 NP_002782 NR_104110
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Subcellular Location Cytoplasm. Nucleus. Cytoplasm, P-body {ECO:0000250}. Note=Colocalizes with TRIM5 in the cytoplasmic bodies. {ECO:0000250}.
Top Pathways Proteasome

PSMA6 Antibody - 2459 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using PMSA6 Antibody.

20S Proteasome α6 (H-135) - sc-67343 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
20S Proteasome α6 (H-135): sc-67343. Western blot analysis of 20S Proteasome α6 expression in HeLa (A), Hep G2 (B) and MCF7 (C) nuclear extracts and Hep G2 (D) whole cell lysate.

20S Proteasome α6 (C-5) - sc-271187 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
20S Proteasome α6 (C-5): sc-271187. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic and nuclear localization.

20S Proteasome α6 (G-12) - sc-54724 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

20S Proteasome α6 (S-15) - sc-54674 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

20S Proteasome α6 (MCP20) - sc-58416 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
20S Proteasome α6 (MCP20): sc-58416. Western blot analysis of 20S Proteasome α6 expression in HeLa whole cell lysate.

Anti-Proteasome subunit alpha type 6 antibody - ab185731 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human stomach cancer tissue labelling Proteasome subunit alpha type 6 with ab185731 at 1/200. Magnification: 400x.

Anti-Proteasome subunit alpha type 6 antibody - ab140443 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Proteasome subunit alpha type 6 antibody (ab140443) at 0.1 µg/mlLane 1 : 293T whole cell lysate at 50 µgLane 2 : 293T whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 50 µgLane 4 : Jurkat whole cell lysate at 50 µgLane 5 : NIH 3T3 whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-Proteasome subunit alpha type 6 antibody - ab196614 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Proteasome subunit alpha type 6 antibody (ab196614) at 1/500 dilutionLane 1 : HepG2 cell lysateLane 2 : HeLa cell lysateLane 3 : HL60 cell lysateLane 4 : monkey COS7 cell lysateLane 5 : rat PC12 cell lysateLane 6 : MCF7 cell lysateLane 7 : A375 cell lysateLane 8 : NCL-H460 cell lysateLane 9 : mouse skeletal muscle lysate

Anti-Proteasome subunit alpha type 6 antibody - ab97563 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Proteasome subunit alpha type 6 antibody (ab97563) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLane 3 : H1299 whole cell lysateLane 4 : HeLa whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Proteasome subunit alpha type 6 antibody - ab97562 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Proteasome subunit alpha type 6 antibody (ab97562) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-Proteasome subunit alpha type 6 antibody - ab197292 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-Proteasome subunit alpha type 6 antibody (ab197292) at 1/1000 dilution + 293T cell lysate

Anti-Proteasome subunit alpha type 6 antibody - ab167312 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Proteasome subunit alpha type 6 antibody (ab167312) at 1 µg/ml + Human liver lysate at 50 µg

Anti-Proteasome subunit alpha type 6 antibody [4C9] - ab128490 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4C9
All lanes : Anti-Proteasome subunit alpha type 6 antibody [4C9] (ab128490) at 1/500 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cells transfected with pCMV6-ENTRY Proteasome subunit alpha type 6 cDNALysates/proteins at 5 µg per lane.

Anti-Proteasome subunit alpha type 6 antibody [EPR5834] - ab124887 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5834
All lanes : Anti-Proteasome subunit alpha type 6 antibody [EPR5834] (ab124887) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : HeLa cell lysateLane 3 : HepG2 cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Proteasome subunit alpha type 6 antibody [EPR5835] - ab109377 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5835
All lanes : Anti-Proteasome subunit alpha type 6 antibody [EPR5835] (ab109377) at 1/50000 dilutionLane 1 : HepG2 cell lysateLane 2 : 293T cell lysateLane 3 : HeLa cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.

Anti-PSMA6 Antibody (clone 5H3) - LS-C174611 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5H3
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PSMA6 mouse monoclonal antibody.

Anti-PSMA6 Antibody (clone 7C2) - LS-C175133 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7C2
IHC of paraffin-embedded Human pancreas tissue using anti-PSMA6 mouse monoclonal antibody.

Anti-PSMA6 Antibody (clone 4C9) - LS-C174610 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4C9
IHC of paraffin-embedded Carcinoma of Human prostate tissue using anti-PSMA6 mouse monoclonal antibody.

Anti-PSMA6 Antibody (N-Terminus) - LS-C201386 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human HepG2. PSMA6 antibody dilution 1.0 ug/ml.

Anti-PSMA6 Antibody - LS-C192881 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of human brain cell lines, using PSMA6 antibody.

Anti-PSMA6 Antibody (clone MCP20) - LS-C343780 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone MCP20

Anti-PSMA6 Antibody (aa196-246) - LS-C290461 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse PSMA6 by Western Blot (h and m) and Immunoprecipitation (h). Samples: Whole cell lysate from 293T (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), HeLa (H; 50 ug), Jurkat (J; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-PSMA6 antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

Anti-PSMA6 Antibody (clone 1A4) - LS-C336920 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PSMA6 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PSMA6.

Anti-PSMA6 Antibody (clone MCP106) - LS-C343807 from LifeSpan Bioscience

Prices $235.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone MCP106
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