CCR3

Gene Symbol CCR3
Entrez Gene 1232
Alt Symbol CC-CKR-3, CD193, CKR3, CMKBR3
Species Human
Gene Type protein-coding
Description chemokine (C-C motif) receptor 3
Other Description C-C CKR-3|C-C chemokine receptor type 3|CC chemokine receptor 3|CCR-3|b-chemokine receptor|eosinophil CC chemokine receptor 3|eosinophil eotaxin receptor
Swissprots Q8TDP6 Q2YDB9 Q86WD2 Q15748 P51677 F5GWL6 B3KVQ1 Q9ULY8
Accessions AAB09726 AAB16831 AAL85154 AAO65970 ABK41943 BAA86964 CAD88095 CAR96700 EAW64758 EAW64759 P51677 AF026535 AAB82589 AF224495 AAK49027 AF262299 AAL85628 AF262300 AAL85629 AF262301 AAL85630 AF262302 AAL85631 AF262303 AAL85632 AF262304 BC110297 AAI10298 BC130318 AAI30319 BC130320 AAI30321 HQ258185 ADR82939 U28694 AAC50469 XM_006712960 XP_006713023 XM_011533334 XP_011531636 XM_011533335 XP_011531637 NM_001164680 NP_001158152 NM_001837 NP_001828 NM_178328 NP_847898 NM_178329 NP_847899
Function Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity In eosinophils as well as trace amounts in neutrophils and monocytes.
Top Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Viral carcinogenesis

CKR-3 (5E8) - sc-32777 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CKR-3 (5E8): sc-32777. Western blot analysis of CKR-3 expression in human PBL whole cell lysate.

CKR-3 (C-20) - sc-6225 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CKR-3 (H-52) - sc-7897 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CKR-3 (S-17) - sc-31559 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CCR3 antibody - ab36827 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-CCR3 antibody (ab36827) at 1 µg/mlLanes 2 - 3 : Anti-CCR3 antibody (ab36827) at 2 µg/mlLane 1 : Human spleen tissue lysates Lane 2 : Human spleen tissue lysates Lane 3 : Human spleen tissue lysates with Blocking peptide

Anti-CCR3 antibody - ab1667 from Abcam

Prices $379.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunocytochemistry on human peripheral blood cells (acetone fixed cells).

Anti-CCR3 antibody - ab36829 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-CCR3 antibody (ab36829) at 1 µg/mlLanes 2 - 3 : Anti-CCR3 antibody (ab36829) at 2 µg/mlLane 1 : Human spleen tissue lysatesLane 2 : Human spleen tissue lysatesLane 3 : Human spleen tissue lysates with blocking peptideLysates/proteins at 15 µg per lane.

Anti-CCR3 antibody - ab157139 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-CCR3 antibody (ab157139) at 1/1000 dilutionLane 1 : HeLa total cell extractLane 2 : Jurkat total cell extractLane 3 : Mouse thymus total cell extractLane 4 : Mouse heart total cell extractLane 5 : Mouse kidney total cell extract

Anti-CCR3 antibody - ab112515 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CCR3 antibody (ab112515) at 1 µg/mlLane 1 : Spleen (Human) Tissue Lysate - adult normal tissue (ab29699)Lane 2 : Thymus (Human) Tissue Lysate - adult normal tissue (ab30146)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CCR3 antibody - ab115285 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human tonsil tissue (lymphocytes; formalin-fixed, paraffin-embedded) stained with ab115285 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-CCR3 antibody [5E8] - ab16231 from Abcam

Prices $379.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5E8
ICC/IF image of ab16231 stained Hek293 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab16231, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-mouse IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-CCR3 antibody [5E8] (Biotin) - ab16581 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5E8

Anti-CCR3 antibody [5E8-G9-B4], prediluted (Allophycocyanin) - ab155356 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 5E8-G9-B4
Flow cytometric analysis of normal Human peripheral blood cells labeling CCR3 with Anti-Human CD16 PE and mouse IgG2b kappa Isotype Control APC (left) or 5 µl (0.25 µg) of ab155356 (right). Cells in the large scatter population were used for analysis.

Anti-CCR3 antibody [Y31] - ab32512 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y31
Immunohistochemical analysis of paraffin-embedded human liver tissue using ab32512 at 1/100 dilution.

Anti-CCR3 antibody [Y31] (HRP) - ab200020 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y31
All lanes : Anti-CCR3 antibody [Y31] (HRP) (ab200020) at 1/5000 dilutionLane 1 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell LysateLane 2 : Daudi (Human Burkitt's lymphoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-CCR3 antibody - C-terminal - ab151623 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CCR3 antibody - C-terminal (ab151623) at 1/1000 dilution + K562 whole cell lysate at 30 µg

Anti-CCR3 antibody - N-terminal - ab189346 from Abcam

Prices $378.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed paraffin-embedded Human skin tissue labeling CCR3 with ab189346 at 5 µg/ml.

Anti-CCR3 Antibody (Extracellular Domain) IHC-plus™ - LS-A1386 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CCR3 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CCR3 Antibody (N-Terminus) IHC-plus™ - LS-B3185 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CCR3 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3185 concentration 5 ug/ml.

Anti-CCR3 Antibody (aa1-20) - LS-C313284 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
CCR3 antibody. IHC(P): Human Tonsil Tissue.

Anti-CCR3 Antibody (C-Terminus) IHC-plus™ - LS-A1389 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CCR3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CCR3 Antibody (C-Terminus) - LS-C4353 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCR3 Antibody (aa8-34) - LS-C4380 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-CCR3 Antibody (Azide-free) - LS-C19359 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCR3 Antibody - LS-C649 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of 10 ug of total cell lysate from Daudi cells with antibody at 2 ug/ml dilution.
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