ITPR1

Gene Symbol ITPR1
Entrez Gene 3708
Alt Symbol ACV, CLA4, INSP3R1, IP3R, IP3R1, PPP1R94, SCA15, SCA16, SCA29
Species Human
Gene Type protein-coding
Description inositol 1,4,5-trisphosphate receptor, type 1
Other Description IP3 receptor|IP3R 1|inositol 1,4,5-triphosphate receptor, type 1|inositol 1,4,5-trisphosphate receptor type 1|protein phosphatase 1, regulatory subunit 94|type 1 InsP3 receptor|type 1 inositol 1,4,5-trisphosphate receptor
Swissprots Q14643 Q14660 E9PDE9 Q99897 E7EPX7
Accessions EAW63908 EAW63909 EAW63910 EAW63911 EAW63912 EAW63913 EAW63914 EAW63915 Q14643 AB208868 BAD92105 AI470158 AK293752 BAG57174 AK294594 BAG57782 AK296235 BAG58955 AK309981 AK311008 AW501800 BC144563 AAI44564 BG202086 BM695661 BQ006717 CN431631 CV355426 D26070 BAA05065 DA060305 DB260851 DB544988 DB576768 L38019 AAB04947 S82269 AAD14386 U23850 XM_005265109 XP_005265166 XM_005265110 XP_005265167 XM_006713131 XP_006713194 XM_011533681 XP_011531983 XM_011533682 XP_011531984 XM_011533683 XP_011531985 XM_011533684 XP_011531986 XM_011533685 XP_011531987 XM_011533686 XP_011531988 XM_011533687 XP_011531989 XM_011533688 XP_011531990 XM_011533689 XP_011531991 XM_011533690 XP_011531992 XM_011533691 XP_011531993 XM_011533692 XP_011531994 NM_001099952 NP_001093422 NM_001168272 NP_001161744 NM_002222 NP_002213
Function Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity Widely expressed.
Top Pathways Inflammatory mediator regulation of TRP channels, Estrogen signaling pathway, Oxytocin signaling pathway, cGMP-PKG signaling pathway, Thyroid hormone synthesis

Inositol 1, 4, 5-trisphosphate receptor type 1 (ITPR1), Human, ELISA Kit - CSB-EL011912HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

inositol 1, 4, 5-triphosphate receptor, type 1, ELISA Kit - MBS924170 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human ITPR1 is typically less than 1.56 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 6.25 pg/ml -400 pg/ml.

Human Inositol 1,4,5-trisphosphate receptor type 1(ITPR1) ELISA kit - CSB-EL011912HU from Cusabio

Category ELISA Kit
Sensitivity 1.56 pg/ml
Range 6.25 pg/ml-400 pg/ml

Human ITPR1 ELISA Kit - E019859 from Biobool

Category ELISA Kit
Sensitivity The minimum detectable dose of human ITPR1 is typically less than 1.56 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the me

anti-IP3 Receptor antibody - ARG10608 from Arigo Biolaboratories

Category ELISA Kit

ITPR1 ELISA Kit (Human) (OKCA01311) - OKCA01311 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 1.56 pg/mL
Range 6.25 - 400 pg/mL

Inositol 1,4,5,-trisphosphate, ELISA Kit - MBS284725 from MyBioSource

Category ELISA Kit
Prices $465.00, $790.00, $3,500.00, $6,655.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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