ABCB9

Gene Symbol ABCB9
Entrez Gene 23457
Alt Symbol EST122234, TAPL
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family B (MDR/TAP), member 9
Other Description ABC transporter 9 protein|ATP-binding cassette sub-family B member 9|TAP-like protein
Swissprots Q96AB1 Q5W9G7 B4E2J0 Q9NP78 Q769F4 Q769F3 Q9P208
Accessions CAI93387 CAI93388 EAW98353 EAW98354 EAW98355 EAW98356 EAW98357 EAW98358 EAW98359 EAW98360 EAW98361 EAW98362 EAW98363 Q9NP78 AB040953 BAA96044 AB045381 BAA97989 AB112582 BAC98409 AB112583 BAC98410 AB177852 BAD66830 AF216494 AAF89993 AK027624 BAG51360 AK074738 BAC11171 AK294225 BAG57529 AK304295 BAG65152 AL833963 CAD38811 BC017348 AAH17348 BC064384 AAH64384 CA503047 DA796102 U66676 XM_005253558 XP_005253615 XM_011538095 XP_011536397 XM_011538096 XP_011536398 XM_011538097 XP_011536399 XM_011538098 XP_011536400 XM_011538099 XP_011536401 XR_429086 XR_944513 NM_001243013 NP_001229942 NM_001243014 NP_001229943 NM_019624 NP_062570 NM_019625 NP_062571 NM_203444 NP_982269 NM_203445
Function ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored. {ECO:0000269|PubMed:15863492, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18434309}.
Subcellular Location Lysosome membrane {ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:15577206, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18175933, ECO:0000269|PubMed:18952056, ECO:0000269|PubMed:20377823, ECO:0000269|PubMed:21212514}; Multi- pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:15577206, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18175933, ECO:0000269|PubMed:18952056, ECO:0000269|PubMed:20377823, ECO:0000269|PubMed:21212514}. Note=May be located in membrane rafts.
Tissue Specificity Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid. Not expressed in monocytes but strongly expressed during differentiation of monocytes to dendritic cells and macrophages. {ECO:0000269|PubMed:10748049, ECO:0000269|PubMed:17977821}.
Top Pathways ABC transporters, Lysosome

ABCB9 CRISPR/Cas9 KO Plasmid (h) - sc-407687 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB9 HDR Plasmid (h) - sc-407687-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB9 Double Nickase Plasmid (h) - sc-407687-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB9 Double Nickase Plasmid (h2) - sc-407687-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB9 CRISPR Activation Plasmid (h) - sc-407687-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB9 CRISPR Activation Plasmid (h2) - sc-407687-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB9 Lentiviral Activation Particles (h) - sc-407687-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB9 Lentiviral Activation Particles (h2) - sc-407687-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ABCB9 siRNA (h) - sc-60115 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ABCB9 shRNA Plasmid (h) - sc-60115-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ABCB9 shRNA (h) Lentiviral Particles - sc-60115-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ABCB9 RNAi - H00023457-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ABCB9 RNAi - H00023457-R07 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU132641 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2632 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2632 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ABCB9 siRNA (Human) - CRH8281 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCB9 RNAi - H00023457-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ABCB9 RNAi - H00023457-R08 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ABCB9 - MBS8232307 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ABCB9 (NM_019625.3) - SHH229058 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ABCB9(NM_019624.3) - SHG023599 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ABCB9(NM_019625.3) - SHG023635 from Creative biogene

Category siRNA
Species Reactivities Human

ABCB9 shRNA Plasmid (Human) - CHH8281 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ABCB9 miRNA 3'UTR clone - MiUTR1H-00033 from Creative biogene

Species Reactivities Human
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