| Gene Symbol |
TMOD4
|
| Entrez Gene |
29765
|
| Alt Symbol |
SK-TMOD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tropomodulin 4 (muscle)
|
| Other Description |
actin-capping protein|skeletal muscle tropomodulin|tropomodulin-4
|
| Swissprots |
B7Z6N9 Q9NZQ9 Q5JR83 Q8WVL3 Q9UKH2
|
| Accessions |
AAK06765 AAM73676 EAW53463 EAW53464 EAW53465 Q9NZQ9 AF165217 AAF01277 AF177173 AAF31672 AK092700 BAC03951 AK300675 BAH13325 AK313280 BAG36088 BC017810 AAH17810 BX647346 DC385872 HQ447602 ADQ32088 XM_005245104 XP_005245161 XM_011509449 XP_011507751 NM_013353 NP_037485
|
| Function |
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton.
|
| Subcellular Location |
Cytoplasm, cytoskeleton. Note=In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments (PubMed:25250574). {ECO:0000269|PubMed:25250574}.
|
| Tissue Specificity |
Highly expressed in skeletal muscle. {ECO:0000269|PubMed:10662549}.
|