| Gene Symbol |
Col2a1
|
| Entrez Gene |
12824
|
| Alt Symbol |
Col2, Col2a, Col2a-1, Del1, Dmm, Lpk, M100856, Rgsc856
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
collagen, type II, alpha 1
|
| Other Description |
alpha-1 type II collagen|chondrocalcin|collagen alpha-1(II) chain|disproportionate micromelia|procollagen, type II, alpha 1
|
| Swissprots |
Q80X38 Q62033 Q62032 Q80VY3 Q8CEF7 Q61428 Q62031 Q6LDB1 Q641K3 Q8K0N6 P28481 Q6LDI8 Q6LDI9
|
| Accessions |
AAA37435 AAA37436 AAA68099 AAA68100 AAA68101 AAA68102 AAB19627 AAC06113 CAA41047 EDL04212 EDL04213 P28481 AK028295 BAC25865 AK053784 AK132311 BC030913 AAH30913 BC051383 AAH51383 BC052326 AAH52326 BC082331 AAH82331 CF728108 CJ306441 XM_006520386 XP_006520449 NM_001113515 NP_001106987 NM_031163 NP_112440
|
| Function |
Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}.
|
| Top Pathways |
Focal adhesion, ECM-receptor interaction, Amoebiasis, Protein digestion and absorption, PI3K-Akt signaling pathway
|