DGKQ

Gene Symbol DGKQ
Entrez Gene 1609
Alt Symbol DAGK, DAGK4, DAGK7
Species Human
Gene Type protein-coding
Description diacylglycerol kinase, theta 110kDa
Other Description DAG kinase theta|DGK-theta|diacylglycerol kinase theta|diglyceride kinase theta
Swissprots Q6P3W4 P52824
Accessions EAW82630 EAW82631 EAW82632 P52824 AB209503 BAD92740 AW139889 BC063801 AAH63801 DN990411 DQ596864 GU727647 ADU87648 L38707 AAA98749 XM_011513411 XP_011511713 XM_011513412 XP_011511714 XM_011513413 XP_011511715 XM_011513414 XP_011511716 XM_011513415 XP_011511717 NM_001347 NP_001338
Function Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor (By similarity). May be involved in cAMP- induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity. {ECO:0000250, ECO:0000269|PubMed:17664281}.
Subcellular Location Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton. Nucleus. Nucleus speckle. Note=Translocates to the nucleus in response to thrombin stimulation (By similarity). Translocates to the plasma membrane in response to steroid hormone receptor stimulation. Translocation to the plasma membrane is dependent on G-protein coupled receptor stimulation and subsequent activation of PRKCE and probably PRKCH. {ECO:0000250}.
Top Pathways Choline metabolism in cancer, Glycerolipid metabolism, Glycerophospholipid metabolism, Phosphatidylinositol signaling system

Human DGKQ ELISA Kit (Cell-Based ELISA) - LS-F3129 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate

DGKQ Colorimetric Cell-Based ELISA - CB5921 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

diacylglycerol kinase, theta 110kDa, ELISA Kit - MBS9343286 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DGKQ ELISA Kit - DEIA-XYA545 from Creative Diagnostics

Category ELISA Kit

Human DGKQ ELISA Kit - E011856 from Biobool

Category ELISA Kit

Human Diacylglycerol kinase alpha (DGKA) ELISA Kit - AE47369HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t

Human Diacylglycerol kinase theta (DGKQ) ELISA Kit - AE47358HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t

DGKQ Colorimetric Cell-Based ELISA Kit - EKA50779 from Biomatik

Category ELISA Kit
Prices $399.00
Sizes 96 tests
Sensitivity At least 5000 cells/well
Range Qualitative
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