BDH2

Gene Symbol BDH2
Entrez Gene 56898
Alt Symbol DHRS6, EFA6R, PRO20933, SDR15C1, UCPA-OR, UNQ6308
Species Human
Gene Type protein-coding
Description 3-hydroxybutyrate dehydrogenase, type 2
Other Description 3-hydroxybutyrate dehydrogenase type 2|R-beta-hydroxybutyrate dehydrogenase|dehydrogenase/reductase (SDR family) member 6|dehydrogenase/reductase SDR family member 6|oxidoreductase UCPA|short chain dehydrogenase/reductase family 15C member 1|short chain dehydrogenase/reductase family 15C, member 1
Swissprots Q6IA46 Q503A0 Q9BUT1 Q6UWD3 Q9NRX8 B4DUF6 Q9H8S8 A8K295
Accessions CAC43884 CBF99640 CBG07667 CBG14351 CBV13160 CBV21189 CBV27865 EAX06163 EAX06164 EAX06165 EAX06166 EAX06167 EAX06168 Q9BUT1 AF164790 AAF80754 AK023323 BAB14526 AK128463 BAG54681 AK290160 BAF82849 AK291335 BAF84024 AK300626 BAG62318 AW136198 AY358841 AAQ89200 BC001953 AAH01953 BC037277 AAH37277 BC095414 AAH95414 BI544872 CR457309 CAG33590 XM_005263140 XP_005263197 XM_006714274 XP_006714337 XM_011532127 XP_011530429 XM_011532128 XP_011530430 NM_020139 NP_064524
Function Dehydrogenase that mediates the formation of 2,5- dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16380372}.
Top Pathways Synthesis and degradation of ketone bodies, Butanoate metabolism

DHRS6 (E-4) - sc-393030 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DHRS6 (E-4): sc-393030. Western blot analysis of DHRS6 expression in Caki-1 (A) and IMR-32 (B) whole cell lysates.

DHRS6 (H-2) - sc-514288 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DHRS6 (H-2): sc-514288. Western blot analysis of DHRS6 expression in Caki-1 (A), IMR-32 (B), Jurkat (C) and Hep G2 (D) whole cell lysates and human kidney tissue extract (E).

DHRS6 (H-5) - sc-393008 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DHRS6 (H-5): sc-393008. Western blot analysis of DHRS6 expression in non-transfected 293T: sc-117752 (A), mouse DHRS6 transfected 293T: sc-119767 (B), Caki-1 (C) and IMR-32 (D) whole cell lysates.

DHRS6 (G-14) - sc-104196 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DHRS6 (G-14): sc-104196. Western blot analysis of DHRS6 expression in non-transfected: sc-117752 (A) and mouse DHRS6 transfected: sc-119767 (B) 293T whole cell lysates.

DHRS6 (T-20) - sc-104197 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DHRS6 (T-20): sc-104197. Western blot analysis of DHRS6 expression in non-transfected 293T: sc-117752 (A), mouse DHRS6 transfected 293T: sc-119767 (B), Caki-1 (C) and IMR-32 (D) whole cell lysates.

Anti-BDH2 antibody - ab69161 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-BDH2 antibody (ab69161) at 1/500 dilution + human kidney tissue lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-BDH2 antibody [4G4] - ab119029 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4G4
All lanes : Anti-BDH2 antibody [4G4] (ab119029) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY BDH2 cDNALysates/proteins at 5 µg per lane.

Anti-BDH2 Antibody (aa92-103) - LS-C61712 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-BDH2 Antibody - LS-C306537 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-BDH2 Antibody (aa143-192) - LS-C112042 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BDH2 antibody LS-C112042 Western blot of Jurkat lysate.

Anti-BDH2 Antibody (aa60-71) IHC-plus™ - LS-B10295 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-BDH2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10295 concentration 5 ug/ml.

Anti-BDH2 Antibody (clone 3G10) - LS-C115301 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3G10
IHC of paraffin-embedded Human thyroid tissue using anti-BDH2 mouse monoclonal antibody. (Dilution 1:50).

Anti-BDH2 Antibody (clone 2G1) - LS-C115302 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2G1
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-BDH2 mouse monoclonal antibody. (Dilution 1:50).

BDH2 Antibody (2G1) - NBP2-02651 from Novus Biologicals

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2G1

BDH2 Antibody - NBP2-32713 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BDH2 Antibody [NBP2-32713] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10Lane 2: Human Kidney tissue

BDH2 Antibody - NB100-93379 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

BDH2 Antibody - H00056898-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: BDH2 Antibody [H00056898-B01] - DHRS6 MaxPab polyclonal antibody (B01), Lot # 08077 WULz. Western Blot analysis of DHRS6 expression in human kidney.

Anti-BDH2 antibody produced in rabbit - HPA036028 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BDH2: <B>Cat. No. HPA036028</B>: Immunohistochemical staining of human duodenum shows strong cytoplasmic and nuclear positivity in glandular cells.

Anti-BDH2 antibody produced in rabbit - SAB2106103 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-BDH2: <B>Cat. No. SAB2106103</B>: BDH2 in Jurkat cell lysates with BDH2 antibody at 1.0 μg/mL.

Anti-BDH2/DHRS6 (AA 60-71) antibody produced in goat - SAB2500156 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-BDH2 / DHRS6 (aa 60 to 71): <B>Cat. No. SAB2500156</B>: (0.3 μg/mL) staining of Human Kidney lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-BDH2 (63-74) antibody produced in rabbit - SAB1102356 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human BDH2 was separated on SDS-PAGE, blotted with Anti-BDH2 (63-74) (<B>Cat. No. SAB1102356</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500 <BR/>2. Antibody dilution 1:500 + BDH2 immunizing peptide (human, 63-74)

Monoclonal Anti-BDH2 antibody produced in mouse - SAB4100130 from Sigma-Aldrich

Prices $358.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone BDH2-A112
<B>Immunofluorescence</B><BR/>U87 cells were fixed and permeabilized with 4% Paraformaldehyde and 0.5% Triton X-100. Fixed cells were stained with Mouse Anti-BDH2 Clone: BDH2-A112 (<B>Cat. No. SAB4100130</B>) diluted to 1:50. The antibody was developed using Goat Anti-Mouse IgG, Cy3 conjugate. Cells were counterstained with DAPI (blue) to stain nuclei.

BDH2 antibody - middle region (ARP57360_P050) - ARP57360_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BDH2--DHRS6-aa-92-to-103-Antibody-internal-region - AF2710a from Abgent, a WuXi AppTec company

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

BDH2--DHRS6-aa-60-to-71-Antibody - AF1148a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1148a (0.3 µg/ml) staining of Human Kidney lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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