Il6

Gene Symbol	Il6
Entrez Gene	16193
Alt Symbol	Il-6
Species	Mouse
Gene Type	protein-coding
Description	interleukin 6
Other Description	B-cell hybridoma growth factor|interleukin HP-1|interleukin-6
Swissprots	P08505 Q8BN26 Q3UCQ0
Accessions	AAA39302 AAA68814 CAA35824 EDL37257 EDL37258 P08505 AK089780 AK150440 BAE29562 AK152189 BAE31020 BC132458 AAI32459 BC138766 AAI38767 BC145409 DQ788722 ABG81953 J03783 AAA39301 X06203 CAA29560 X54542 CAA38411 NM_031168 NP_112445
Function	Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig- secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. {ECO:0000269|PubMed:16990136}.
Subcellular Location	Secreted.
Top Pathways	TNF signaling pathway, Legionellosis, Herpes simplex infection, PI3K-Akt signaling pathway, African trypanosomiasis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant Mouse IL-6 Protein - NBP2-35134 from Novus Biologicals Category Protein Prices $69.00, $169.00, $529.00, $2,669.00 Sizes 2 µg, 10 µg, 100 µg, 1 mg Source E. coli

IL-6 Recombinant Protein - P4364 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Mouse

IL-6 Protein - NBP1-99234 from Novus Biologicals Category Protein Prices $299.00 Sizes 10 µg Species Mouse

IL-6 Protein - NBP1-43220 from Novus Biologicals Category Protein Prices $289.00 Sizes 5 µg Species Mouse

IL-6 Protein - NBP1-42921 from Novus Biologicals Category Protein Prices $1,149.00 Sizes 100 µg Species Mouse

IL6 protein - GTX29731 from GeneTex Category Protein Prices $239.00 Sizes 10 μg Species Mouse, Rat

IL6 recombinant protein - GTX65360 from GeneTex Category Protein Prices $249.00 Sizes 10 μg Source E. coli Species Mouse

IL6 Recombinant Protein (Active) - GTX48301-PRO from GeneTex Category Protein Prices $299.00 Sizes 10 μg Source E. coli Species Mouse

Recombinant Mouse IL-6 - 406-ML-005 from R&D Systems Category Protein Source E. coli-derived, Phe25-Thr211, with an N-terminal Met

Recombinant Mouse IL-6 - 406-ML-025 from R&D Systems Category Protein Source E. coli-derived, Phe25-Thr211, with an N-terminal Met

Recombinant Mouse IL-6 - 406-ML-200 from R&D Systems Category Protein Source E. coli-derived, Phe25-Thr211, with an N-terminal Met

Recombinant Mouse IL-6, CF - 406-ML-005/CF from R&D Systems Category Protein Source E. coli-derived, Phe25-Thr211, with an N-terminal Met

Recombinant Mouse IL-6, CF - 406-ML-025/CF from R&D Systems Category Protein Source E. coli-derived, Phe25-Thr211, with an N-terminal Met

Recombinant Mouse IL-6, CF - 406-ML-200/CF from R&D Systems Category Protein Source E. coli-derived, Phe25-Thr211, with an N-terminal Met

IL 6 Protein (OPPA00613) - OPPA00613 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Mouse IL-6 R protein - orb163552 from Biorbyt Category Protein Prices $408.00, $595.00, $2,074.00, $2,933.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source E. coli Species Mouse

Mouse IL6 protein - orb97798 from Biorbyt Category Protein Prices $451.00 Sizes 10 μg Source P08505 Species Escherichia coli

Mouse IL-6 protein - orb180556 from Biorbyt Category Protein Prices $391.00 Sizes 10 μg Source E. coli Species Mouse

Mouse B cell differentiation factor protein - orb139206 from Biorbyt Category Protein Prices $179.00, $400.00, $731.00 Sizes 5 μg, 20 μg, 100 μg Source E. coli Species Mouse

IL6 protein - 30R-2493 from Fitzgerald Category Protein Prices $265.00 Sizes 10 µg Source E.coli Species Mouse

IL6 protein (His tag) - 80R-3963 from Fitzgerald Category Protein Prices $375.00 Sizes 100 µg Source E.coli

IL6 protein (Mouse) - 30R-2163 from Fitzgerald Category Protein Prices $300.00, $795.00 Sizes 5 µg, 25 µg Source E.coli Species Mouse

IL6 protein (Mouse) - 30R-AI081 from Fitzgerald Category Protein Prices $95.00, $225.00 Sizes 2 µg, 10 µg Source E.coli Species Mouse

IL6 protein (Mouse) - 30R-2247 from Fitzgerald Category Protein Prices $1,595.00 Sizes 100 µg Source E.coli Species Mouse

Mouse IL-6 Protein (Recombinant) - abx060801 from Abbexa Category Protein Source Mouse Species Mouse

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