COPB2

Gene Symbol COPB2
Entrez Gene 9276
Alt Symbol beta'-COP
Species Human
Gene Type protein-coding
Description coatomer protein complex, subunit beta 2 (beta prime)
Other Description beta'-coat protein|betaprime-COP|coatomer binding complex, beta prime subunit|coatomer subunit beta'|p102
Swissprots B4DZI8 P35606
Accessions CAJ42726 EAW79039 EAW79040 P35606 AK128561 AK302943 BAG64100 AK304219 BAG65091 BC000326 AAH00326 DC347783 DC385126 JF432305 ADZ15522 X70476 CAA49900 XM_011513317 XP_011511619 NM_004766 NP_004757 NR_023350
Function The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Shows only a slight preference for the cis-Golgi apparatus, compared with the trans-Golgi. {ECO:0000250}.

β’-COP siRNA (h) - sc-41200 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

β’-COP shRNA Plasmid (h) - sc-41200-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

β’-COP shRNA (h) Lentiviral Particles - sc-41200-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

COPB2 RNAi - H00009276-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU033981 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6427 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6427 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01853 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01853

COPB2 siRNA (Human) - CRH6142 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

COPB2 - MBS8217537 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human COPB2 (NM_004766.2) - SHH267749 from Creative biogene

Category siRNA
Species Reactivities Human

COPB2 shRNA Plasmid (Human) - CHH6142 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

COPB2 miRNA 3'UTR clone - MiUTR3H-08876 from Creative biogene

Species Reactivities Human
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