FTH1

Gene Symbol FTH1
Entrez Gene 2495
Alt Symbol FHC, FTH, FTHL6, HFE5, PIG15, PLIF
Species Human
Gene Type protein-coding
Description ferritin, heavy polypeptide 1
Other Description apoferritin|cell proliferation-inducing gene 15 protein|ferritin H subunit|ferritin heavy chain|placenta immunoregulatory factor|proliferation-inducing protein 15
Swissprots Q3SWW1 P02794 B3KNR5 Q3KRA8
Accessions AAA52438 ABF47097 CAA27205 CAP19952 EAW73989 EAW73990 EAW73991 EAW73992 EAW73993 EAW73994 EAW73995 EAW73996 EAW73997 EAW73998 EAW73999 EAW74000 EAW74001 P02794 AB062402 BAB93489 AF088851 AAF89523 AK311818 AY258285 AAP82230 BC000857 AAH00857 BC001399 AAH01399 BC011359 AAH11359 BC013724 AAH13724 BC015156 AAH15156 BC015946 BC016009 AAH16009 BC016857 AAH16857 BC020300 BC035441 BC063514 AAH63514 BC066341 AAH66341 BC066961 AAH66961 BC070494 AAH70494 BC073750 AAH73750 BC104643 AAI04644 BC105802 AAI05803 BM971420 BQ887222 D28463 BAA05829 DQ891113 ABM82039 DQ894293 ABM85219 L20941 AAA35833 M11146 AAA52437 M12937 AAA35830 M15383 AAA52479 M97164 AAA35832 X00318 CAA25086 NM_002032 NP_002023
Function Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in the liver. {ECO:0000269|PubMed:11389486}.
Top Pathways Mineral absorption

FTH1 Antibody - 3998 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HT-29 and HeLa cells using FTH1 Antibody.

FTH1 (D1D4) Rabbit mAb - 4393 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D1D4
Western blot analysis of extracts from HeLa and HT-29 cells using FTH1 (D1D4) Rabbit mAb.

ferritin (05) - sc-80786 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

ferritin heavy chain (B-12) - sc-376594 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ferritin heavy chain (B-12): sc-376594. Western blot analysis of ferritin heavy chain expression in Hep G2 whole cell lysate.

ferritin heavy chain (H-53) - sc-25617 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ferritin heavy chain (H-53): sc-25617. Immunoper-oxidase staining of formalin fixed, paraffin-embedded human liver tissue showing membrane and cytoplasmic staining of hepatocytes.

ferritin heavy chain (Y-16) - sc-14416 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ferritin heavy chain (Y-16): sc-14416. Western blot analysis of ferritin heavy chain expression in Daudi (A), Hep G2 (B) and Caco-2 (C) whole cell lysates.

ferritin heavy chain (3F8) - sc-135667 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
ferritin heavy chain (3F8): sc-135667. Western blot analysis of ferritin heavy chain expression in U87-MG (A) and HeLa (B) whole cell lysates.

Anti-Ferritin, mitochondrial antibody - ab66111 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC-Fr image of Ferritin, mitochondrial staining on mouse skeletal muscle using ab66111 (1: 100). The sections were fixed in 4% PFA and the section was permeabilized using 0.1% TritonX in 0.1% PBS. The section was then blocked using 10% conkey serum for 1 hour at 24°C. The primary antibody (1:100) was incubated at 4°C for 24 hours and the secondary antibody used was donkey polyclonal to rabbit IgG conjugated to Alexa Fluor 488 (1:1000).

Anti-Ferritin, mitochondrial antibody - ab31662 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab31662 stained HeLa cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab31662, 1æg/ml) overnight at +4øC. The secondary antibody (green)ÿwas Alexa Fluor© 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor© 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43æM.

Anti-Ferritin, mitochondrial antibody - ab31153 from Abcam

Host Duck
Clonality Polyclonal

Anti-Ferritin, mitochondrial antibody - ab76768 from Abcam

Prices $372.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-Ferritin, mitochondrial antibody - ab93428 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Ferritin, mitochondrial antibody (ab93428) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : HEK293 (Human embryonic kidney cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Ferritin, mitochondrial antibody - ab33574 from Abcam

Prices $370.00
Sizes 200 µg
Host Goat
Clonality Polyclonal

Anti-Ferritin, mitochondrial antibody - ab33624 from Abcam

Prices $370.00
Sizes 500 µg
Host Chicken
Clonality Polyclonal

Anti-Ferritin, mitochondrial antibody [057-10010] - ab30749 from Abcam

Prices $372.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone 057-10010

Anti-Ferritin, mitochondrial antibody [057-10030] - ab30904 from Abcam

Prices $370.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone 057-10030

Anti-Ferritin, mitochondrial antibody (Biotin) - ab7333 from Abcam

Prices $359.00
Sizes 2 mg
Host Rabbit
Clonality Polyclonal

Anti-Ferritin, mitochondrial antibody [F23] - ab10060 from Abcam

Prices $376.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone F23
ICC/IF image of ab10060 stained Hek293 cells. The cells were 4% PFA fixed (10 min) and then incubated in 1%BSA / 10% normal Goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab10060, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 Goat anti-Mouse IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Ferritin, mitochondrial antibody [F31] (HRP) - ab24475 from Abcam

Prices $370.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone F31

Anti-Ferritin, mitochondrial antibody (HRP) - ab31996 from Abcam

Prices $372.00
Sizes 1 mg
Host Rabbit
Clonality Polyclonal

Anti-Ferritin, mitochondrial antibody (HRP) - ab7334 from Abcam

Prices $359.00
Sizes 1 mg
Host Rabbit
Clonality Polyclonal

Anti-Ferritin, mitochondrial antibody, prediluted - ab76769 from Abcam

Prices $370.00
Sizes 7 ml
Host Rabbit
Clonality Polyclonal

Anti-Ferritin antibody - ab124383 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab124383, at 1/100 dilution, staining Ferritin in formalin-fixed, paraffin-embedded Human fetal brain tissue by Immunohistochemistry.

Anti-Ferritin antibody [18B8] - ab181706 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 18B8

Anti-Ferritin antibody [3F8] - ab134276 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone 3F8
Immunohistochemical analysis of paraffin-embedded Human liver tissue labelling Ferritin with ab134276 at 1/200. Primary incubation was followed by biotinylated horse anti-mouse IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
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