JAG2

Gene Symbol JAG2
Entrez Gene 3714
Alt Symbol HJ2, SER2
Species Human
Gene Type protein-coding
Description jagged 2
Other Description protein jagged-2
Swissprots Q9UE99 Q9Y6P9 Q9Y219 Q9Y6Q0 Q9UNK8 Q9UE17
Accessions AAD15562 EAW81899 EAW81900 EAW81901 Q9Y219 AA775404 AB209370 BAD92607 AF003521 AAB61285 AF020201 AAB71189 AF029778 AAB84215 AF029779 AAB84216 AI276672 AJ712299 BC032053 BX105691 LN607838 CEF49525 U69180 Y14330 CAA74706 XM_011536736 XP_011535038 NM_002226 NP_002217 NM_145159 NP_660142
Function Putative Notch ligand involved in the mediation of Notch signaling. Involved in limb development (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney.
Top Pathways Notch signaling pathway

Jagged2 (C83A8) Rabbit mAb - 2205 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C83A8
Western blot analysis of total cell lysates from HeLa, SK-OV-3 and SR cells using Jagged2 (C83A8) Rabbit mAb.

Jagged2 (C23D2) Rabbit mAb - 2210 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C23D2
Western blot analysis of total cell lysates from HeLa, SK-OV-3 and SR cells using Jagged2 (C23D2) Rabbit mAb.

Jagged2 (H-143) - sc-5604 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Jagged2 (H-143): sc-5604. Western blot analysis of human recombinant Jagged2 fusion protein.

Jagged2 (C-17) - sc-8157 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Jagged2 (C-17): sc-8157. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

Jagged2 (N-19) - sc-34475 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Jagged2 (N-19): sc-34475. Western blot analysis of Jagged2 expression in mouse placenta tissue extract.

Jagged2 (S-16) - sc-34476 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Jagged2 (S-16): sc-34476. Western blot analysis of human recombinant Jagged2 fusion protein.

Anti-Jagged 2 antibody - ab60041 from Abcam

Prices $382.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ab60041 at 1/50-1/100 dilution staining Jagged 2 in Human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. The primary antibody was peroxidase-conjugated to the secondary antibody, followed by AEC staining.

Anti-Jagged 2 antibody - ab61175 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-Jagged 2 antibody (ab61175) at 1 µg/ml + Recombinant protein at 0.2 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

Anti-Jagged 2 antibody - ab10556 from Abcam

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot for Jagged 2 antibody (ab10556) at 1/500 tested on the following tissue lysates:Lane 1: Mouse BrainLane 2: Mouse LungLane 3: Rat BrainLane 4: Rat LungLane 5: Mouse Brain Day 0Secondary ab: Goat anti-rabbit IgG ab6721 (1/5000)Exposure time: 10 minutesExpected molecular weight: 130 kDaCell lysates at 20µg per lane.NB: This image shows that is was not possible to detect Jagged 2 by WB in the lysates tested. This maybe due to low expression/abundance of Jagged 2 compounded by the fact that Jagged 2 expression is developmentally regulated and induced making it difficult to detect in whole tissue homogenates. In favour of the Jagged 2 antibody (ab10556), this WB shows relatively low background and minimal cross reactivity in tissue lysate.

Anti-Jagged 2 antibody - ab55257 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-Jagged 2 antibody - ab80671 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Jagged 2 antibody (ab80671) at 1 µg/ml + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Jagged 2 antibody [EPR3646] - ab109627 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3646
All lanes : Anti-Jagged 2 antibody [EPR3646] (ab109627) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : HUVEC cell lysateLane 3 : HT-29 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti-Rabbit at 1/2000 dilution

Anti-JAG2 / Jagged-2 Antibody (aa1224-1238) - LS-C3002 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-JAG2 / Jagged-2 Antibody (aa111-128) - LS-C18928 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-JAG2 / Jagged-2 Antibody (Ala117) - LS-C37093 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal

Anti-JAG2 / Jagged-2 Antibody (Pro1212) - LS-C37094 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal

Anti-JAG2 / Jagged-2 Antibody (clone 12G33) - LS-C182620 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Hamster
Clonality Monoclonal
Clone 12G33

Anti-JAG2 / Jagged-2 Antibody (clone 12G34) - LS-C182621 from LifeSpan Bioscience

Prices $445.00
Sizes 250 µg
Host Hamster
Clonality Monoclonal
Clone 12G34

Anti-JAG2 / Jagged-2 Antibody (aa1-307, clone 11n117, APC) - LS-C184834 from LifeSpan Bioscience

Prices $590.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone 11n117

Anti-JAG2 / Jagged-2 Antibody (aa1-307, clone 11n117, PE) - LS-C184835 from LifeSpan Bioscience

Prices $530.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone 11n117

Anti-JAG2 / Jagged-2 Antibody (N-Terminus) - LS-C80702 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.

Anti-JAG2 / Jagged-2 Antibody (clone HMJ2-1) - LS-C188669 from LifeSpan Bioscience

Prices $235.00
Sizes 100 µg
Host Hamster
Clonality Monoclonal
Clone HMJ2-1

Anti-JAG2 / Jagged-2 Antibody (Internal) - LS-C210136 from LifeSpan Bioscience

Prices $295.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-JAG2 / Jagged-2 Antibody (C-Terminus, AP) - LS-C278601 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-JAG2 / Jagged-2 Antibody (C-Terminus, APC) - LS-C278602 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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