ABI2

Gene Symbol	ABI2
Entrez Gene	10152
Alt Symbol	ABI-2, ABI2B, AIP-1, AblBP3, SSH3BP2, argBP1, argBPIA, argBPIB
Species	Human
Gene Type	protein-coding
Description	abl-interactor 2
Other Description	abelson interactor 2|abl binding protein 3|abl interactor 2|abl-interacting protein 1 (SH3-containing protein)|abl-interactor protein 2b|arg protein tyrosine kinase-binding protein|arg-binding protein 1
Swissprots	B4DSN1 Q13801 Q13249 Q9BV70 Q13147 Q9NYB9
Accessions	AAY14675 AAY14935 EAW70335 EAW70336 EAW70337 EAW70338 EAW70339 EAW70340 EAW70341 EAW70342 EAW70343 Q9NYB9 AF085867 AF260261 AAF70308 AK054863 AK294429 BAG57674 AK297537 BAG59937 AK299092 BAH12947 AK299672 BAH13098 AK299679 BAG61587 AK299688 BAH13103 AK299750 BAG61640 AK299824 BAG61693 AK302853 BAH13822 AK311427 AK316000 BAH14371 AK316343 BAH14714 BC001439 AAH01439 BC033944 BT009920 AAP88922 CN371368 DA693234 DB455742 DC376086 DQ890735 ABM81661 DQ893907 ABM84833 R61525 U23435 AAA92289 U31089 AAA75446 X95632 CAA64885 XM_005246217 XP_005246274 XM_005246218 XP_005246275 XM_005246221 XP_005246278 XM_005246222 XP_005246279 XM_005246225 XP_005246282 XM_005246226 XP_005246283 XM_006712174 XP_006712237 XM_006712177 XP_006712240 XM_006712178 XP_006712241 XM_006712179 XP_006712242 XM_006712180 XP_006712243 XM_006712181 XP_006712244 XM_006712182 XP_006712245 XM_006712183 XP_006712246 XM_006712185 XP_006712248 XM_006712186 XP_006712249 XM_011510472 XP_011508774 XM_011510473 XP_011508775 XM_011510474 XP_011508776 NM_001282925 NP_001269854 NM_001282926 NP_001269855 NM_001282927 NP_001269856 NM_001282932 NP_001269861 NM_005759 NP_005750
Function	May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. {ECO:0000269|PubMed:10498863, ECO:0000269|PubMed:7590236, ECO:0000269|PubMed:8649853}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Top Pathways	Regulation of actin cytoskeleton

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ABI2 protein fragment - ab127336 from Abcam Category Protein Prices $364.00 Sizes 50 µg Source E. coli Species Human

ABI2B / ABI2 Antibody Blocking Peptide - LS-E1770 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ABI2B / ABI2 Antibody Blocking Peptide - LS-E22458 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ABI2 Protein - H00010152-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

ABI2-Antibody-N-term-Blocking-peptide - BP12566a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ABI2 - H00010152-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

ABI2 fusion protein - Ag6679 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

ABI2 fusion protein - Ag7024 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human ABI2, GST-tagged - ABI2-9247H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Abl interactor 2(ABI2) - CSB-YP001102HU CSB-EP001102HU CSB-BP001102HU CSB-MP001102HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Abl interactor homolog(abiA) - MBS1422706 from MyBioSource Category Protein Prices $2,140.00, $2,140.00, $2,605.00, $2,605.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ABI2 - TP300637 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ABI2 Recombinant Protein Antigen - NBP2-49637PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

ABI2 Peptide, Human - M34GP00091H from Creative Peptides Category Peptide Source Synthetic. Species Human

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