FXYD2

Gene Symbol FXYD2
Entrez Gene 486
Alt Symbol ATP1G1, HOMG2
Species Human
Gene Type protein-coding
Description FXYD domain containing ion transport regulator 2
Other Description ATPase, Na+/K+ transporting, gamma 1 polypeptide|Na(+)/K(+) ATPase subunit gamma|sodium pump gamma chain|sodium/potassium-transporting ATPase subunit gamma
Swissprots Q9GZQ7 P54710 Q15332 Q9GZP3 Q53YC1
Accessions AAG34359 AAG34360 AAG37906 AAG37907 EAW67325 EAW67326 P54710 AA309757 AA814197 AF241236 AAG34361 AK096069 BAC04693 BC005302 AAH05302 BC013289 AAH13289 BT006721 AAP35367 BX641053 DQ786191 U50743 AAB09425 NM_001680 NP_001671 NM_021603 NP_067614 NM_001127489
Function May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
Subcellular Location Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}.
Tissue Specificity Expressed in the distal convoluted tubule in the kidney. Found on basolateral membranes of nephron epithelial cells.
Top Pathways Salivary secretion, Cardiac muscle contraction, cAMP signaling pathway, Aldosterone-regulated sodium reabsorption, Thyroid hormone synthesis