| Gene Symbol |
FXYD2
|
| Entrez Gene |
486
|
| Alt Symbol |
ATP1G1, HOMG2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
FXYD domain containing ion transport regulator 2
|
| Other Description |
ATPase, Na+/K+ transporting, gamma 1 polypeptide|Na(+)/K(+) ATPase subunit gamma|sodium pump gamma chain|sodium/potassium-transporting ATPase subunit gamma
|
| Swissprots |
Q9GZQ7 P54710 Q15332 Q9GZP3 Q53YC1
|
| Accessions |
AAG34359 AAG34360 AAG37906 AAG37907 EAW67325 EAW67326 P54710 AA309757 AA814197 AF241236 AAG34361 AK096069 BAC04693 BC005302 AAH05302 BC013289 AAH13289 BT006721 AAP35367 BX641053 DQ786191 U50743 AAB09425 NM_001680 NP_001671 NM_021603 NP_067614 NM_001127489
|
| Function |
May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Expressed in the distal convoluted tubule in the kidney. Found on basolateral membranes of nephron epithelial cells.
|
| Top Pathways |
Salivary secretion, Cardiac muscle contraction, cAMP signaling pathway, Aldosterone-regulated sodium reabsorption, Thyroid hormone synthesis
|