IMPA1

Gene Symbol IMPA1
Entrez Gene 3612
Alt Symbol IMP, IMPA
Species Human
Gene Type protein-coding
Description inositol(myo)-1(or 4)-monophosphatase 1
Other Description D-galactose 1-phosphate phosphatase|IMP 1|IMPase 1|inositol monophosphatase 1|inositol-1(or 4)-monophosphatase 1|lithium-sensitive myo-inositol monophosphatase A1
Swissprots Q9UK71 P29218 J3KQT7 B7Z6Q4 B2R733 B4DLN3
Accessions AAD52997 CAA72195 EAW87095 EAW87096 EAW87097 EAW87098 EAW87099 EAW87100 P29218 AF042729 AAB97468 AI921211 AK297078 BAG59595 AK300750 BAH13340 AK312823 BAG35680 BC008381 AAH08381 BC009565 AAH09565 BP270804 DB299262 DC375686 HQ447127 ADQ31614 X66922 CAA47359 NM_001144878 NP_001138350 NM_001144879 NP_001138351 NM_005536 NP_005527
Function Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo- inositol monophosphates, myo-inositol 1,3-diphosphate, myo- inositol 1,4-diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1- phosphate, beta-glycerophosphate, and 2'-AMP as substrates. {ECO:0000269|PubMed:17068342, ECO:0000269|PubMed:8718889, ECO:0000269|PubMed:9462881}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17068342}.
Top Pathways Inositol phosphate metabolism, Phosphatidylinositol signaling system

IMPA1 (A-2) - sc-373733 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IMPA1 (A-2): sc-373733. Western blot analysis of IMPA1 expression in HCT 116 (A) and HS 181.Tes (B) whole cell lysates.

IMPA1 (H-7) - sc-374234 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IMPA1 (H-7): sc-374234. Western blot analysis of IMPA1 expression in HCT 116 (A) and HS 181.Tes (B) whole cell lysates.

IMPA1 (T-18) - sc-50599 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IMPA1 (H-85) - sc-99227 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
IMPA1 (H-85): sc-99227. Western blot analysis of IMPA1 expression in PC-3 (A) and IMR-32 (B) whole cell lysates.

IMPA1 (N-18) - sc-50596 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-IMPA1 [EPR15405] antibody - ab191570 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15405
Flow cytometric analysis of PC3 cells labeling IMPA1 using ab191570at 1/300 dilution (red), Isotype control (green). Secondary antibody was Goat anti rabbit IgG (FITC) at 1/150 dilution. Cells were fixed in 2% paraformaldehyde prior to staining.

Anti-IMPA1 antibody - ab202131 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of A549 cells labeling IMPA1 with ab202131. Counter-stained with DAPI for nuclear staining.

Anti-IMPA1 antibody - ab73074 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IMPA1 antibody (ab73074) at 1 µg/mlLane 1 : Liver (Mouse) Tissue Lysate Lane 2 : Testis (Human) Tissue Lysate - adult normal tissue (ab30257)Lane 3 : SK N SH (Human neuroblastoma) Whole Cell Lysate Lane 4 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate Lane 5 : Thymus (Rat) Tissue Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-IMPA1 antibody - ab154372 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IMPA1 antibody (ab154372) at 1/1000 dilutionLane 1 : Jurkat whole cell lysateLane 2 : Raji whole cell lysateLysates/proteins at 30 µg per lane.

Anti-IMPA1 antibody - ab126230 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IMPA1 antibody (ab126230) at 1/1000 dilutionLane 1 : PC3 whole cell lysateLane 2 : SK N SH whole cell lysateLysates/proteins at 30 µg per lane.

Anti-IMPA1 antibody [EPR15404(B)] - ab184165 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15404(B)
All lanes : Anti-IMPA1 antibody [EPR15404(B)] (ab184165) at 1/50000 dilutionLane 1 : Human testis tissue lysateLane 2 : Jurkat cell line lysateLane 3 : PC 3 cell line lysateLane 4 : HCT116 cell line lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated antibody at 1/1000 dilution

Anti-IMPA1 / IMP Antibody - LS-C311280 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IMPA1 / IMP Antibody (C-Terminus) - LS-C112233 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
IMPA1 antibody LS-C112233 Western blot of Fetal Heart lysate.

Anti-IMPA1 / IMP Antibody (clone 1E6-F11) - LS-C197531 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1E6-F11
Detection limit for recombinant GST tagged IMPA1 is 0.1 ng/ml as a capture antibody.

Anti-IMPA1 / IMP Antibody - LS-C334674 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using IMPA1 antibody.

IMPA1 Antibody - NBP1-83107 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: IMPA1 Antibody [NBP1-83107] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

IMPA1 Antibody - H00003612-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: IMPA1 Antibody [H00003612-A01] - A1 polyclonal antibody (A01), Lot # Abnova060509QCS1 Western Blot analysis of IMPA1 expression in NIH/3T3 ( Cat # L018V1 ).

IMPA1 Antibody - NBP2-16963 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: IMPA1 Antibody [NBP2-16963] - Sample (30 ug of whole cell lysate) A: PC-3 B: SK-N-SH 12% SDS PAGE gel, diluted at 1:1000.

IMPA1 Antibody - NBP2-16964 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: IMPA1 Antibody [NBP2-16964] - Sample (30 ug of whole cell lysate) A: JurKat B: Raji 12% SDS PAGE gel, diluted at 1:1000.

IMPA1 Antibody - H00003612-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: IMPA1 Antibody [H00003612-D01P] - Analysis of IMPA1 expression in Raw 264.7.

IMPA1 Antibody - H00003612-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: IMPA1 Antibody [H00003612-B01] - analysis of IMPA1 expression in transfected 293T cell line by IMPA1 MaxPab polyclonal antibody (B01). Lane 1: IMPA1 transfected lysate (30.20 KDa). Lane 2: Non-transfected lysate.

IMPA1 Antibody (1E6-F11) - H00003612-M01A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 1E6-F11

IMPA1 Antibody (1E6-F11) - H00003612-M01 from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1E6-F11
Sandwich ELISA: IMPA1 Antibody (1E6-F11) [H00003612-M01] - Detection limit for recombinant GST tagged IMPA1 is 0.1 ng/ml as a capture antibody.

Anti-IMPA1 antibody produced in rabbit - SAB1410714 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-IMPA1: <B>Cat. No. SAB1410714</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~30.2 kDa using Raw 264.7 lysate.

Anti-IMPA1 antibody produced in rabbit - HPA037489 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-IMPA1: <B>Cat. No. HPA037489</B>: Immunohistochemical staining of human testis shows strong cytoplasmic and nuclear positivity in seminiferous tubules.
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