GAD2

Gene Symbol GAD2
Entrez Gene 2572
Alt Symbol GAD65
Species Human
Gene Type protein-coding
Description glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Other Description 65 kDa glutamic acid decarboxylase|GAD-65|Glutamate decarboxylase-2 (pancreas)|glutamate decarboxylase 2|glutamate decarboxylase 65 kDa isoform
Swissprots Q05329 Q9UD87
Accessions AAP88040 EAW86101 EAW86102 EAW86103 EAW86104 Q05329 AJ251501 CAB62572 AK127375 BAC86947 BC029517 AAH29517 BC039038 BC047899 BC126327 AAI26328 BC126329 AAI26330 BI438818 BP392604 HQ258311 ADR83065 M74826 AAA58491 M81882 AAA62367 X69936 NM_000818 NP_000809 NM_001134366 NP_001127838
Function Catalyzes the production of GABA.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:12356867}. Cytoplasmic vesicle {ECO:0000269|PubMed:12356867}. Cell junction, synapse, presynaptic cell membrane {ECO:0000269|PubMed:12356867}; Lipid-anchor {ECO:0000269|PubMed:12356867}. Golgi apparatus membrane {ECO:0000269|PubMed:12356867}; Peripheral membrane protein {ECO:0000269|PubMed:12356867}; Cytoplasmic side {ECO:0000269|PubMed:12356867}. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.
Top Pathways Type I diabetes mellitus, GABAergic synapse, Taurine and hypotaurine metabolism, Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism

GAD-65 CRISPR/Cas9 KO Plasmid (h) - sc-402137 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAD-65 HDR Plasmid (h) - sc-402137-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAD-65 Double Nickase Plasmid (h) - sc-402137-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAD-65 Double Nickase Plasmid (h2) - sc-402137-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAD-65 CRISPR Activation Plasmid (h) - sc-402137-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAD-65 CRISPR Activation Plasmid (h2) - sc-402137-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAD-65 Lentiviral Activation Particles (h) - sc-402137-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAD-65 Lentiviral Activation Particles (h2) - sc-402137-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GAD-65 siRNA (h) - sc-41964 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GAD-65 shRNA Plasmid (h) - sc-41964-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GAD-65 shRNA (h) Lentiviral Particles - sc-41964-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU018781 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9061 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9061 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04811 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04811

GAD2 siRNA (Human) - CRH1710 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GAD2 - MBS8202875 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human GAD2 siRNA - orb262212 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GAD2 shRNA Plasmid (Human) - CHH1710 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GAD2 miRNA 3'UTR clone - MiUTR3H-00897 from Creative biogene

Species Reactivities Human

GAD2 miRNA 3'UTR clone - MiUTR3H-00898 from Creative biogene

Species Reactivities Human
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