ABCB11

Gene Symbol ABCB11
Entrez Gene 8647
Alt Symbol ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family B (MDR/TAP), member 11
Other Description ABC member 16, MDR/TAP subfamily|ATP-binding cassette sub-family B member 11|bile salt export pump|progressive familial intrahepatic cholestasis 2|sister p-glycoprotein
Swissprots O95342 Q9UNB2 Q53TL2
Accessions AAY24100 AAY24305 CAI54162 CAI54163 EAX11285 EAX11286 EAX11287 O95342 AB012959 BAA88711 AF091582 AAC77455 AF136523 AAD28285 AK302540 BAG63812 AK303050 BAG64170 XM_006712817 XP_006712880 XM_011512077 XP_011510379 XM_011512078 XP_011510380 XM_011512079 XP_011510381 XM_011512080 XP_011510382 XM_011512081 XP_011510383 NM_003742 NP_003733
Function Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ.
Top Pathways ABC transporters, Bile secretion

BSEP CRISPR/Cas9 KO Plasmid (h) - sc-400742 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BSEP HDR Plasmid (h) - sc-400742-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BSEP Double Nickase Plasmid (h) - sc-400742-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BSEP Double Nickase Plasmid (h2) - sc-400742-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BSEP CRISPR Activation Plasmid (h) - sc-400742-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BSEP CRISPR Activation Plasmid (h2) - sc-400742-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BSEP Lentiviral Activation Particles (h) - sc-400742-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BSEP Lentiviral Activation Particles (h2) - sc-400742-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BSEP siRNA (h) - sc-41157 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BSEP shRNA Plasmid (h) - sc-41157-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BSEP shRNA (h) Lentiviral Particles - sc-41157-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ABCB11 RNAi - H00008647-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU041451 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® 3′UTR Lenti GoClone™ - HUTR06047 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06047

ABCB11 siRNA (Human) - CRH5685 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCB11 - MBS8233880 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BSEP CRISPR/Cas9 KO Plasmid (h2) - sc-400742-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BSEP HDR Plasmid (h2) - sc-400742-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human ABCB11 (NM_003742.2) - SHH228970 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ABCB11(NM_003742.2) - SHG023389 from Creative biogene

Category siRNA
Species Reactivities Human

Human ABCB11 siRNA - orb266187 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCB11 shRNA Plasmid (Human) - CHH5685 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ABCB11 miRNA 3'UTR clone - MiUTR1H-00027 from Creative biogene

Species Reactivities Human
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