APLNR

Gene Symbol	APLNR
Entrez Gene	187
Alt Symbol	AGTRL1, APJ, APJR, HG11
Species	Human
Gene Type	protein-coding
Description	apelin receptor
Other Description	APJ (apelin) receptor|APJ receptor|G protein-coupled receptor APJ|G-protein coupled receptor APJ|G-protein coupled receptor HG11|HG11 orphan receptor|angiotensin II receptor-like 1|angiotensin receptor-like 1
Swissprots	P35414
Accessions	AAA18954 EAW73730 P35414 AK074514 BAC11032 AK075252 BAG52096 AK097232 BAG53437 AK315542 BAG37920 AL548962 AL553350 BC032688 AAH32688 BI004477 BM698661 BX439288 DQ890844 ABM81770 EU176506 ABW03307 X89271 CAA61546 NM_005161 NP_005152 NR_027991
Function	Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.
Top Pathways	Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human APJ Receptor peptide - ab101728 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

APLNR/ Apelin Receptor / APJ Antibody Blocking Peptide - LS-E2993 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APLNR/ Apelin Receptor / APJ Antibody Blocking Peptide - LS-E21964 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APLNR/ Apelin Receptor / APJ Antibody Blocking Peptide - LS-E21963 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

APLNR/ Apelin Receptor / APJ Antibody Blocking Peptide - LS-E29116 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

APLNR/ Apelin Receptor / APJ Antibody Blocking Peptide - LS-E29119 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

APLNR/ Apelin Receptor / APJ Antibody Blocking Peptide - LS-E29132 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

APJ/Apelin receptor Recombinant Protein - H00000187-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 25 ug 10 ug Species Human

APLNR-Antibody-Center-Blocking-peptide - BP14123c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

APLNR Blocking Peptide - 33R-4779 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

APJ Blocking Peptide - abx062014 from Abbexa Category Peptide Species Human, Mouse, Rat, Chicken

Apelin Receptor - H00000187-G01 from Acris Antibodies Category Protein Prices $440.00 Sizes 2 µg Species Human

Apelin Receptor - H00000187-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

APJ, Blocking Peptide - 214-10026 from RayBiotech Category Peptide

APLNR fusion protein - Ag14138 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

APLNR fusion protein - ag16830 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human APLNR, GST-tagged - APLNR-9744H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human APLNR, His-tagged - APLNR-3550H from Creative Biomart Category Protein Source E. Coli or Yeast Species Human

Recombinant Apelin Receptor (APLNR) - RPD067Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

ChemiSCREEN™ Membrane Preparation Recombinant Human APJ Apelin Receptor - HTS068M from EMD Millipore Prices $596.00 Sizes 200 units Species Human

APJ Blocking Peptide - CBP3120 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Chicken

APLNR (C181) Peptide - BS2584P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human APJ/Apelin receptor Protein - H00000187-G01 from Novus Biologicals Category Protein Prices $415.00 Sizes 2 µg Source Wheat Germ Species Human

Apelin Receptor - TP307576 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Apelin receptor (APLNR), Recombinant Protein - MBS717761 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast Species Human

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