ADRA2A

Gene Symbol ADRA2A
Entrez Gene 150
Alt Symbol ADRA2, ADRA2R, ADRAR, ALPHA2AAR, ZNF32
Species Human
Gene Type protein-coding
Description adrenoceptor alpha 2A
Other Description adrenergic, alpha-2A-, receptor|alpha-2 adrenergic receptor subtype C10|alpha-2-adrenergic receptor, platelet type|alpha-2A adrenergic receptor|alpha-2A adrenoceptor|alpha-2A adrenoreceptor|alpha-2AAR subtype C10
Swissprots Q86TH8 P08913 Q2I8G2 Q2XN99 B0LPF6 Q9BZK1
Accessions AAA51664 AAA51665 AAF91441 AAG00447 AAK01634 AAK51162 AAZ73101 ABB72683 ABY87535 EAW49547 P08913 AF284095 AAK26743 BC035047 AAH35047 BC050414 AAH50414 BM682651 NM_000681 NP_000672
Function Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol. {ECO:0000269|PubMed:23105096}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:23105096}; Multi-pass membrane protein {ECO:0000269|PubMed:23105096}.
Top Pathways cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction

α 2A -AR CRISPR/Cas9 KO Plasmid (h) - sc-401545 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2A -AR HDR Plasmid (h) - sc-401545-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2A -AR Double Nickase Plasmid (h) - sc-401545-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2A -AR Double Nickase Plasmid (h2) - sc-401545-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2A -AR CRISPR Activation Plasmid (h) - sc-401545-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2A -AR CRISPR Activation Plasmid (h2) - sc-401545-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2A -AR Lentiviral Activation Particles (h) - sc-401545-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2A -AR Lentiviral Activation Particles (h2) - sc-401545-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

α 2A -AR siRNA (h) - sc-39862 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

α 2A -AR shRNA Plasmid (h) - sc-39862-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

α 2A -AR shRNA (h) Lentiviral Particles - sc-39862-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

alpha-2A Adrenergic R/ADRA2A RNAi - H00000150-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ZNF32 RNAi - H00007580-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ZNF32 RNAi - H00007580-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN1775 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1775 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09356 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09356

ADRA2A siRNA (Human) - CRH0104 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ADRA2A - MBS8204781 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ADRA2A (NM_000681.3) - SHH232706 from Creative biogene

Category siRNA
Species Reactivities Human

ADRA2A shRNA Plasmid (Human) - CHH0104 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ADRA2A miRNA 3'UTR clone - MiUTR3H-00110 from Creative biogene

Species Reactivities Human
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