PSMC3

Gene Symbol PSMC3
Entrez Gene 5702
Alt Symbol TBP1
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) 26S subunit, ATPase, 3
Other Description 26S protease regulatory subunit 6A|26S proteasome AAA-ATPase subunit RPT5|TBP-1|Tat-binding protein 1|human immunodeficiency virus tat transactivator binding protein-1|proteasome 26S subunit ATPase 3|proteasome subunit P50
Swissprots Q3B757 Q53HU5 B2R8V1 Q6IBS1 Q6GPG8 Q3B865 P17980 Q96HD3
Accessions EAW67916 P17980 AK222485 BAD96205 AK291896 BAF84585 AK313518 BAG36298 BC008713 AAH08713 BC073165 AAH73165 BC106920 AAI06921 BC107804 AAI07805 BP284685 CR456731 CAG33012 DQ892981 ABM83907 DQ896229 ABM87228 M34079 AAA36666 XM_011520232 XP_011518534 XM_011520233 XP_011518535 NM_002804 NP_002795
Function The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). In case of HIV-1 infection, suppresses Tat-mediated transactivation. {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}. Cytoplasm, P-body {ECO:0000250}. Note=Colocalizes with TRIM5 in the cytoplasmic bodies. {ECO:0000250}.
Top Pathways Proteasome, Epstein-Barr virus infection

PSMC3/TBP1 Antibody - 13923 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using PSMC3/TBP1 Antibody.

PSMC3 (28-K) - sc-100462 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
PSMC3 (28-K): sc-100462. Western blot analysis of PSMC3 expression in HeLa whole cell lysate.

PSMC3 (N-19) - sc-79588 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PSMC3 antibody - ab96558 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PSMC3 antibody (ab96558) at 1/5000 dilution + Molt-4 whole cell lysate at 30 µg

Anti-PSMC3 antibody - ab154928 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PSMC3 antibody (ab154928) at 1/5000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLane 3 : HepG2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-PSMC3 antibody - ab185730 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab185730. Blue DAPI for nuclear staining.

Anti-PSMC3 antibody - ab125164 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PSMC3 antibody (ab125164) at 0.1 µg/mlLane 1 : 293T whole cell lysate at 50 µgLane 2 : 293T whole cell lysate at 15 µgLane 3 : Jurkat whole cell lysate at 50 µgLane 4 : HeLa whole cell lysate at 50 µgLane 5 : NIH3T3 whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-PSMC3 antibody - ab83348 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PSMC3 antibody (ab83348) at 1 µg/ml + placenta lysate at 10 µg with skim milk/ PBS at 5 %SecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PSMC3 antibody - ab3321 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot on partially purified human 19S proteasome using ab3321.

Anti-PSMC3 antibody - ab58104 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PSMC3 antibody [9G5] - ab117947 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9G5
All lanes : Anti-PSMC3 antibody [9G5] (ab117947) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY PSMC3 cDNALysates/proteins at 5 µg per lane.

Anti-PSMC3 antibody [EPR12152] - N-terminal - ab171969 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12152
Western blot analysis on immunoprecipitation pellet from (Lane 1) HeLa cell lysate or (Lane 2) 1X PBS (negative control) using ab171969 at a 1/10 dilution and HRP-conjugated anti-rabbit IgG preferentially detecting the non-reduced form of rabbit IgG.

Anti-PSMC3 antibody [EPR12153] - ab171974 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12153
Lane 1 : Lane 2 : Lane 3 : Lane 1 : 293T cell lysateLane 2 : HeLa cell lysateLane 3 : HepG2 cell lysateLysates/proteins at 10 µg per lane.

Anti-PSMC3 Antibody (aa72-121) - LS-C112167 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PSMC3 antibody LS-C112167 Western blot of Fetal Lung lysate.

Anti-PSMC3 Antibody (aa101-134) - LS-C102755 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PSMC3 antibody LS-C102755 Western blot of Placenta lysate.

Anti-PSMC3 Antibody (aa293-339) - LS-C30961 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
PSMC3 antibody LS-C30961 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-PSMC3 Antibody (clone 9G5) - LS-C114987 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9G5
Anti-PSMC3 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PSMC3.

Anti-PSMC3 Antibody (Val306) - LS-C192095 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSMC3 Antibody (aa70-119) - LS-C116982 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PSMC3 antibody LS-C116982 Western blot of NCI-H226 cell lysate.

Anti-PSMC3 Antibody (aa271-320) - LS-C119605 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from K562/HT-29 cells, using PRS6A Antibody. The lane on the right is treated with the synthesized peptide.

Anti-PSMC3 Antibody (aa339-389) - LS-C290204 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMC3 Antibody (aa389-439) - LS-C290205 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PSMC3 Antibody (clone 1C10) - LS-C114986 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C10
IHC of paraffin-embedded endometrium tissue using anti-PSMC3 mouse monoclonal antibody. (Dilution 1:50).

Anti-PSMC3 Antibody (clone 8D6) - LS-C114984 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 8D6
IHC of paraffin-embedded Adenocarcinoma of ovary tissue using anti-PSMC3 mouse monoclonal antibody. (Dilution 1:50).

Anti-PSMC3 / Rpt5 Antibody (aa53-152, Azide-free) - LS-C330599 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
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