ENG

Gene Symbol ENG
Entrez Gene 2022
Alt Symbol END, HHT1, ORW1
Species Human
Gene Type protein-coding
Description endoglin
Other Description CD105 antigen
Swissprots Q14926 Q14248 P17813 Q5T9C0
Accessions AAC32802 AAC63386 ABI75346 EAW87702 EAW87703 EAW87704 P17813 AK222669 AK223044 BAD96764 AK290389 BAF83078 AK300156 BAG61940 AK301171 BAH13421 AK302455 BAG63750 BC014271 AAH14271 BC020391 BC031967 BT006872 AAP35518 DA943458 DB079257 DQ893673 ABM84599 DQ895827 ABM86753 J05481 AAA35800 X72012 CAA50891 NM_000118 NP_000109 NM_001114753 NP_001108225 NM_001278138 NP_001265067
Function Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3. {ECO:0000269|PubMed:21737454, ECO:0000269|PubMed:23300529}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Endoglin is restricted to endothelial cells in all tissues except bone marrow.

Endoglin (3A9) Mouse mAb - 14606 from Cell Signaling Technology

Prices $250.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone 3A9
Western blot analysis of extracts from HUVEC cells (+) and A172 cells (-) using Endoglin (3A9) Mouse mAb (upper) or β-Actin (#8457) (lower) as a loading control.

Endoglin (D50G1) Rabbit mAb - 4335 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D50G1
Western blot analysis of extracts from HUVEC cells using Endoglin (D50G1) Rabbit mAb.

Endoglin (A-8) - sc-376381 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Endoglin (A-8): sc-376381. Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta tissue showing membrane staining of trophoblastic cells.

Endoglin (C-20) - sc-19790 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Endoglin (C-20): sc-19790. Western blot analysis of non-reduced Endoglin expression in HL-60 whole cell lysate.

Endoglin (H-300) - sc-20632 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Endoglin (H-300): sc-20632. Western blot analysis of human recombinant Endoglin.

Endoglin (P3D1) - sc-18838 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Endoglin (P3D1): sc-18838. Western blot analysis of Endoglin expression in mouse embryo tissue extract.

Endoglin (43A3) - sc-21787 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Endoglin (43A3): sc-21787. Western blot analysis of Endoglin expression in mouse embryo tissue extract.

Endoglin (8E11) - sc-53999 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Endoglin (P4A4) - sc-20072 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Endoglin (P4A4): sc-20072. Western blot analysis of Endoglin expression in mouse embryo tissue extract.

Endoglin (SN6) - sc-57099 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Endoglin (SN6): sc-57099 Indirect FCM analysis of ECV-304 cells stained with Endoglin (SN6), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-3877.

Endoglin (T-20) - sc-23838 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Endoglin (T-20): sc-23838. Western blot analysis of human recombinant Endoglin.

Anti-CD105 antibody - ab107595 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab107595 staining CD105 in Rat heart cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with formaldehyde, permeabilized with Triton X and blocked with 3% BSA for 1 hour at 25°C. Samples were incubated with primary antibody (1/200) for 1 hour at 25°C. An undiluted FITC-conjugated Goat anti-rabbit IgG polyclonal was used as the secondary antibody.See Abreview

Anti-CD105 antibody - ab49228 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CD105 antibody (ab49228) at 2 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/100000 dilution

Anti-CD105 antibody - ab135528 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CD105 antibody (ab135528) at 1/50 dilution + Mouse heart tissue lysate at 35 µg

Anti-CD105 antibody - ab21224 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Standard Curve for CD105 (Analyte: CD105 protein (ab54338)); dilution range 1pg/ml to 1ug/ml using Capture Antibody Mouse monoclonal [MEM-226] to CD105 (ab2529) at 5ug/ml and Detector Antibody Rabbit polyclonal to CD105 (ab21224) at 0.5ug/ml.

Anti-CD105 antibody - ab137389 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CD105 antibody (ab137389) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg

Anti-CD105 antibody - ab124610 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD105 antibody (ab124610) at 1 µg/mlLane 1 : Heart (Human) Tissue Lysate - adult normal tissueLane 2 : HUVEC (Human Umbilical vein endothelial cell line) Whole Cell LysateLane 3 : Kidney (Human) Tissue Lysate - adult normal tissueLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CD105 antibody - ab85956 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD105 antibody (ab85956) at 1 µg/mlLane 1 : Kidney (Human) Tissue Lysate - adult normal tissue (ab30203)Lane 2 : HUVEC (Human Umbilical Vein Endothelial Cell) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-CD105 antibody - ab74462 from Abcam

Prices $376.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
ab74462, at 1/50 dilution, staining CD105 in formalin fixed, paraffin embedded human tonsil tissue by Immunohistochemistry.

Anti-CD105 antibody [105C02] - ab44967 from Abcam

Prices $373.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 105C02

Anti-CD105 antibody [2H6F11] (OC515) - ab123610 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 2H6F11
ab123610, at 5 µl/106 cells, staining CD105 in Nalm 6 cells by Flow Cytometry. Total cells were used for analysis. Isotype control (blue).

Anti-CD105 antibody [2H6F11] (PerCP) - ab91138 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 2H6F11

Anti-CD105 antibody [2H6F11] (Phycoerythrin) - ab91238 from Abcam

Prices $188.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 2H6F11
ab91238, at 20 µl / 106 cells, staining CD105 in jurkat cell line by Flow cytometry.

Anti-CD105 antibody [2H6F11], prediluted (CF405M) - ab123634 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 2H6F11
Staining of Nalm-6 cell line with ab123634 at 5 µl/106 cells and isotype control IgG1 CFBlue. Total cells were used for analysis.

Anti-CD105 antibody [3A9] - ab114052 from Abcam

Prices $388.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3A9
ab114052, at a 1/200 dilution, staining CD105 in paraffin embedded Human kidney cancer tissue by Immunohistochemistry, with DAB staining.
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