FCGR2B

Gene Symbol	FCGR2B
Entrez Gene	2213
Alt Symbol	CD32, CD32B, FCG2, FCGR2, IGFR2
Species	Human
Gene Type	protein-coding
Description	Fc fragment of IgG, low affinity IIb, receptor (CD32)
Other Description	CDw32|Fc fragment of IgG, low affinity II, receptor for (CD32)|Fc fragment of IgG, low affinity IIb, receptor for (CD32)|Fc gamma RIIb|fc-gamma RII-b|fc-gamma-RIIb|fcRII-b|igG Fc receptor II-b|low affinity immunoglobulin gamma Fc region receptor II-b
Swissprots	Q5VXA9 O95649 P31994 Q53X85 A6H8N3 Q8NIA1
Accessions	ABK41919 BAC54013 BAC54014 BAC54015 BAC54016 BAC54017 BAC54018 BAC54019 BAC54020 EAW90679 EAW90680 EAW90681 EAW90682 P31994 AB050934 BAB92093 AB051387 BAB92094 AB209585 BAD92822 AF543826 AAQ11739 AI692546 AK308150 AW452813 BC031992 AAH31992 BC141826 AAI41827 BC146678 AAI46679 BC148273 AAI48274 CB988406 CR407635 CAG28563 DC381078 DQ894525 ABM85451 H04104 M28696 AAA36051 M31933 AAA35841 M31934 AAA35842 M31935 AAA35843 U87560 AAD00627 U87561 AAD00628 U87562 AAD00629 U87563 AAD00630 U87564 AAD00631 U87565 AAD00632 U87566 AAD00633 U87567 AAD00634 U87568 AAD00635 U87569 AAD00636 U87570 AAD00637 U87571 AAD00638 U87572 AAD00639 U87573 AAD00640 U87574 AAD00641 U87575 AAD00642 U87576 AAD00643 U87577 AAD00644 X17653 CAA35644 X52473 CAA36713 X62573 XM_011509292 XP_011507594 NM_001002273 NP_001002273 NM_001002274 NP_001002274 NM_001002275 NP_001002275 NM_001190828 NP_001177757 NM_004001 NP_003992
Function	Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B- cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Subcellular Location	Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Is the most broadly distributed Fc-gamma- receptor. Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta (endothelial cells). Not detected in natural killer cells.
Top Pathways	B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Phagosome, Staphylococcus aureus infection, Osteoclast differentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human CD32B protein fragment - ab174051 from Abcam Category Protein Prices $372.00 Sizes 100 µg Source HEK 293 cells Species Human

Human CD32B protein fragment - ab137160 from Abcam Category Protein Prices $345.00 Sizes 20 µg Source E. coli Species Human

Human CD32B protein fragment - ab152084 from Abcam Category Protein Prices $188.00 Sizes 10 µg Source HEK 293 cells Species Human

CD32B Antibody Blocking Peptide - LS-E2865 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD32B Antibody Blocking Peptide - LS-E25853 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD32B Antibody Blocking Peptide - LS-E23174 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CD32B Antibody Blocking Peptide - LS-E23173 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Fc gamma RIIB/CD32b Partial Recombinant Protein - H00002213-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Fc gamma RII/CD32 Protein - NBP2-23046 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E.coli Species Human

Fc gamma RIIB/CD32b Recombinant Protein - H00002213-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

Recombinant Human Fc gamma RII/CD32 Protein - P3685 from Novus Biologicals Category Protein Prices $689.00 Sizes 20 µg Source Human Species Human

FCGR2B-Antibody-C-term-Blocking-peptide - BP13987b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CD32B blocking peptide - GTX89542-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human Fc gamma RIIB/C (CD32b/c), CF - 1875-CD-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Ala46-Pro217, with a C-terminal 10-His tag

Human CD32b His tag protein - orb82958 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Cynomolgus CD32b His AVI tag protein - orb84272 from Biorbyt Category Protein Prices $434.00, $646.00 Sizes 50 μg, 100 μg Source Human

Human CD32 protein - orb84269 from Biorbyt Category Protein Prices $434.00, $646.00 Sizes 50 μg, 100 μg Source Human Species Human

Cynomolgus CD32b His tag protein - orb84271 from Biorbyt Category Protein Prices $570.00, $748.00 Sizes 50 μg, 100 μg Source Human

Cynomolgus CD32 protein - orb84386 from Biorbyt Category Protein Prices $434.00, $646.00 Sizes 50 μg, 100 μg Source Human

Human CD32 protein - orb84284 from Biorbyt Category Protein Prices $357.00, $612.00 Sizes 20 μg, 50 μg Source Human Species Human

Human CD32 protein - orb83664 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Insect Species Human

Cynomolgus CD32b His AVI tag protein - orb84290 from Biorbyt Category Protein Prices $400.00, $646.00 Sizes 20 μg, 50 μg Source Cynomolgus Species Human

Human CD32 protein - orb84283 from Biorbyt Category Protein Prices $400.00, $646.00 Sizes 20 μg, 50 μg Source Human Species Human

Human CD32 protein - orb83895 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

Human CD32b His AVI tag protein - orb84278 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Species Human

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