ESRRA

Gene Symbol	ESRRA
Entrez Gene	2101
Alt Symbol	ERR1, ERRa, ERRalpha, ESRL1, NR3B1
Species	Human
Gene Type	protein-coding
Description	estrogen-related receptor alpha
Other Description	ERR-alpha|estrogen receptor-like 1|estrogen-related nuclear receptor alpha|nuclear receptor subfamily 3 group B member 1|steroid hormone receptor ERR1
Swissprots	Q14514 P11474
Accessions	ABF47104 EAW74245 EAW74246 EAW74250 P11474 AB362579 BAF81543 BC007915 AAH07915 BC011528 AAH11528 BC033701 AAH33701 BC063795 AAH63795 BC073956 AAH73956 BC092470 AAH92470 BC093720 AAH93720 BC093722 AAH93722 DB478332 EU446471 ABZ92000 HQ692867 ADZ17378 L38487 AAB17015 X51416 CAA35778 NM_001282450 NP_001269379 NM_001282451 NP_001269380 NM_004451 NP_004442
Function	Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. {ECO:0000269|PubMed:12522104, ECO:0000269|PubMed:16150865, ECO:0000269|PubMed:17676930, ECO:0000269|PubMed:18063693, ECO:0000269|PubMed:23836911, ECO:0000269|PubMed:9271417}.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00407, ECO:0000269|PubMed:18063693}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Estrogen Related Receptor alpha peptide - ab39777 from Abcam Category Peptide Species Human

Human Estrogen Related Receptor alpha protein fragment - ab152370 from Abcam Category Protein Source Wheat germ Species Human

ESRRA / ERR Alpha Antibody Blocking Peptide - LS-E29065 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ESRRA / ERR Alpha Antibody Blocking Peptide - LS-E29072 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ESRRA / ERR Alpha Antibody Blocking Peptide - LS-E11275 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ESRRA / ERR Alpha Antibody Blocking Peptide - LS-E16651 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ESRRA / ERR Alpha Antibody Blocking Peptide - LS-E9690 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ERR alpha/NR3B1 Blocking Peptide - NBP1-47254PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

Recombinant Human ERR alpha/NR3B1 Protein - H00002101-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ERR alpha/NR3B1 Protein - H00002101-P01 from Novus Biologicals Category Protein Prices $305.00, $445.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ESRRA-Antibody-Center-Blocking-Peptide - BP8635c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ESRRA Blocking Peptide - 33R-4336 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Esrra Blocking Peptide - 33R-1216 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Estrogen-related receptor alpha - H00002101-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Estrogen-related receptor alpha - H00002101-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Estrogen-related receptor alpha - H00002101-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Estrogen-related receptor alpha - H00002101-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Estrogen-related receptor alpha Control Peptide - SP5201CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

ERRa fusion protein - ag12042 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ERRa fusion protein - Ag12032 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

ESRRA Peptide - GWB-58SG2W from Genway Biotech Category Peptide Prices $289.00 Sizes 50 µg Source Estrogen-related receptor alpha (ERR alpha), a NR3 Steroid Receptor, was isolated based on sequence similarity in its DNA-binding domain to estrogen receptor alpha (ER alpha). ERR alpha has been shown to regulate the promoters of lactoferrin, medium-chain acyl CoA dehydrogenase, osteopontin, and thyroid receptor alpha, and it may affect cellular energy balance and bone formation. ERR alpha binds as a monodimer to the extended half-site TNAAGGTCA and as a homodimer to the estrogen response elemen

Recombinant Human ESRRA, GST-tagged - ESRRA-123H from Creative Biomart Category Protein Source Sf9 insect cells Species Human

Recombinant Estrogen Related Receptor Alpha (ERRa) - RPD960Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Estrogen Related Receptor Alpha (ERRa) - RPD960Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Estrogen Related Receptor alpha peptide - pep50193 from Covalab Category Peptide Species Human, Mouse, Rat, Pig, Dog

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