ATP6V1G2
| Gene Symbol | ATP6V1G2 |
|---|---|
| Entrez Gene | 534 |
| Alt Symbol | ATP6G, ATP6G2, NG38, VMA10 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| Other Description | ATPase, H+ transporting, lysosomal (vacuolar proton pump)|H(+)-transporting two-sector ATPase, subunit G2|V-ATPase 13 kDa subunit 2|V-type proton ATPase subunit G 2|vacuolar ATP synthase subunit G 2|vacuolar proton pump G subunit 2 |
| Swissprots | O95670 Q5HYU8 B5MEF0 Q5RJ63 Q2L6F8 |
| Accessions | BAB63399 BAC00863 BAC54952 BAD74057 BAD74058 BAE78636 BAF31286 CAA75073 EAX03414 EAX03416 O95670 AA401769 BC047791 BC068023 AAH68023 BC119726 AAI19727 BC119727 AAI19728 BP195978 C20601 NM_001204078 NP_001191007 NM_130463 NP_569730 NM_138282 NP_612139 |
| Function | Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
| Subcellular Location | Melanosome {ECO:0000269|PubMed:17081065}. Note=Highly enriched in late-stage melanosomes. |
| Tissue Specificity | Brain. {ECO:0000269|PubMed:12384298}. |
| Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis |
V-ATPase G2 CRISPR/Cas9 KO Plasmid (h) - sc-408659 from Santa Cruz Biotechnology
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V-ATPase G2 HDR Plasmid (h) - sc-408659-HDR from Santa Cruz Biotechnology
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V-ATPase G2 Double Nickase Plasmid (h) - sc-408659-NIC from Santa Cruz Biotechnology
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V-ATPase G2 Double Nickase Plasmid (h2) - sc-408659-NIC-2 from Santa Cruz Biotechnology
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V-ATPase G2 CRISPR Activation Plasmid (h) - sc-408659-ACT from Santa Cruz Biotechnology
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V-ATPase G2 CRISPR Activation Plasmid (h2) - sc-408659-ACT-2 from Santa Cruz Biotechnology
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V-ATPase G2 Lentiviral Activation Particles (h) - sc-408659-LAC from Santa Cruz Biotechnology
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V-ATPase G2 Lentiviral Activation Particles (h2) - sc-408659-LAC-2 from Santa Cruz Biotechnology
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V-ATPase G2 siRNA (h) - sc-36799 from Santa Cruz Biotechnology
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V-ATPase G2 shRNA Plasmid (h) - sc-36799-SH from Santa Cruz Biotechnology
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V-ATPase G2 shRNA (h) Lentiviral Particles - sc-36799-V from Santa Cruz Biotechnology
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ATP6V1G2 RNAi - H00000534-R02 from Novus Biologicals
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ATP6V1G2 RNAi - H00000534-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN3736 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3736 from Sigma-Aldrich
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ATP6V1G2 siRNA (Human) - CRH0369 from Cohesion Biosciences
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ATP6V1G2 - MBS8205807 from MyBioSource
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shRNA set against Human ATP6V1G2 (NM_130463.3) - SHH243214 from Creative biogene
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ATP6V1G2 shRNA Plasmid (Human) - CHH0369 from Cohesion Biosciences
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ATP6V1G2 miRNA 3'UTR clone - MiUTR3H-08776 from Creative biogene
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ATP6V1G2 miRNA 3'UTR clone - MiUTR3H-08777 from Creative biogene
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