HYAL1

Gene Symbol HYAL1
Entrez Gene 3373
Alt Symbol HYAL-1, LUCA1, MPS9, NAT6
Species Human
Gene Type protein-coding
Description hyaluronoglucosaminidase 1
Other Description hyaluronidase-1|luCa-1|lung carcinoma protein 1|plasma hyaluronidase|tumor suppressor LUCA-1
Swissprots Q8NFK6 Q12794 Q7KYU2 Q9UNI8 Q8NFK5 Q7LE34 Q93013 Q6FH23 Q9UKD5 Q8NFK8 Q6PIZ6 Q8NFK9 Q8NFK7
Accessions AAB67046 AAC02730 EAW65083 EAW65084 EAW65085 EAW65086 EAW65087 EAW65088 EAW65089 EAW65090 EAW65091 Q12794 AF118821 AAD24460 AF173154 AAD53277 AF502904 AAM60770 AF502905 AAM60771 AF502906 AAM60772 AF502907 AAM60773 AF502908 AAM60774 AK097287 BAG53447 AK290816 BAF83505 BC025774 AAH25774 BC035695 AAH35695 CR541933 CAG46731 DA566755 DQ894083 ABM85009 EU176527 ABW03328 U03056 AAD09137 U96078 AAD04190 XM_011533667 XP_011531969 XM_011533668 XP_011531970 XM_011533669 XP_011531971 NM_033159 NP_149349 NM_153281 NP_695013 NM_153282 NP_695014 NM_153283 NP_695015 NM_153285 NP_695017 NR_047690 NM_153284 NM_153286
Function May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth. {ECO:0000269|PubMed:12084718}.
Subcellular Location Secreted {ECO:0000269|PubMed:9223416}. Lysosome {ECO:0000269|PubMed:9223416}.
Tissue Specificity Highly expressed in the liver, kidney and heart. Weakly expressed in lung, placenta and skeletal muscle. No expression detected in adult brain. Isoform 1 is expressed only in bladder and prostate cancer cells, G2/G3 bladder tumor tissues and lymph node specimens showing tumor invasive tumors cells. Isoform 3, isoform 4, isoform 5 and isoform 6 are expressed in normal bladder and bladder tumor tissues. {ECO:0000269|PubMed:10339581, ECO:0000269|PubMed:12084718, ECO:0000269|PubMed:9223416}.
Top Pathways Lysosome, Glycosaminoglycan degradation

HYAL1 (1D10) - sc-101340 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HYAL1 (1D10): sc-101340. Western blot analysis of HYAL1 expression in BHK cell lysate.

HYAL1 (4F9) - sc-101341 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HYAL1 (4F9): sc-101341. Western blot analysis of HYAL1 expression in BHK whole cell lysate.

HYAL1 (H-52) - sc-366416 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

HYAL1 (G-12) - sc-99448 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HYAL1 (G-12): sc-99448. Western blot analysis of HYAL1 expression in COLO 320DM (A), PANC-1 (B) and HEK293 (C) whole cell lysates.

Anti-HYAL1 antibody - ab85375 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HYAL1 antibody (ab85375) at 1 µg/ml (in 5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-HYAL1 antibody - ab203293 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of Formalin-fixed, paraffin embedded Human hepatoma tissue labeling HYAL1 with ab203293 at 1/100 dilution, followed by secondary detection and DAB staining.

Anti-HYAL1 antibody - ab154499 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-HYAL1 antibody (ab154499) at 1/1000 dilution + 293T whole cell lysate at 30 µg

Anti-HYAL1 antibody - ab77489 from Abcam

Prices $369.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-HYAL1 antibody - ab168404 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-HYAL1 antibody (ab168404) at 1 µg/mlLane 1 : HYAL1 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysate

Anti-HYAL1 antibody - ab96751 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-HYAL1 antibody (ab96751) at 1 µg/mlLane 1 : Liver (Human) Tissue Lysate - adult normal tissue (ab29889)Lane 2 : Kidney (Human) Tissue Lysate - adult normal tissue (ab30203)Lane 3 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)Lane 4 : Breast (Human) Tissue Lysate - normal tissue (ab30090)Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-HYAL1 antibody - ab103977 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-HYAL1 antibody (ab103977) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-HYAL1 antibody - ab123789 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-HYAL1 antibody (ab123789) at 1/100 dilution + HepG2 cell line lysate at 35 µg

Anti-HYAL1 antibody [EPR5542] - ab180143 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5542
All lanes : Anti-HYAL1 antibody [EPR5542] (ab180143) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : LnCap cell lysateLane 3 : HT-1376 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-HYAL1 Antibody (clone 2H7) - LS-C197478 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H7
Immunoprecipitation of HYAL1 transfected lysate using anti-HYAL1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with HYAL1 rabbit polyclonal antibody.

Anti-HYAL1 Antibody (aa22-435, Biotin) - LS-C299355 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HYAL1 Antibody (aa52-462, Biotin) - LS-C300716 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HYAL1 Antibody (aa52-462, FITC) - LS-C302128 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HYAL1 Antibody - LS-C308358 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-HYAL1 Antibody (aa22-435, FITC) - LS-C305018 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HYAL1 Antibody (aa279-309) - LS-C322129 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HYAL1 Antibody - LS-C310676 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HYAL1 Antibody (aa52-462) - LS-C294542 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant HYAL1.

Anti-HYAL1 Antibody (aa280-309) - LS-C165092 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HYAL1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-HYAL1 Antibody (aa325-339) IHC-plus™ - LS-B2612 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-HYAL1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2612 concentration 5 ug/ml.

Anti-HYAL1 Antibody (aa434-450) - LS-C343926 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HYAL1 antibody Western blot. Lane 1: NRK Cell Lysate. Lane 2: Mouse Liver Tissue Lysate. Lane 3: Mouse Kidney Tissue Lysate. Lane 4: SP2/0 Cell Lysate.
Search more