BAP1

Gene Symbol BAP1
Entrez Gene 8314
Alt Symbol HUCEP-13, UCHL2, hucep-6
Species Human
Gene Type protein-coding
Description BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
Other Description cerebral protein 6|cerebral protein-13|ubiquitin carboxyl-terminal hydrolase BAP1
Swissprots Q6LEM0 Q7Z5E8 A8K993 Q92560
Accessions EAW65220 EAW65221 Q92560 AB002534 BAB46926 AF045581 AAC15970 AK092725 BAG52602 AK094499 AK225494 AK292608 BAF85297 AK295395 BAG58349 AK307274 AY130008 AAN05092 BC001596 AAH01596 BX647318 D87462 BAA13401 D88812 BAB46921 DA188433 DQ593715 DQ892545 ABM83471 DQ895756 ABM86682 XM_011534149 XP_011532451 XM_011534150 XP_011532452 XM_011534151 XP_011532453 XM_011534152 XP_011532454 NM_004656 NP_004647
Function Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'- linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination. It however does not mediate deubiquitination of BRCA1 and BARD1. Able to mediate autodeubiquitination via intramolecular interactions to couteract monoubiquitination at the nuclear localization signal (NLS), thereby protecting it from cytopl
Subcellular Location Cytoplasm. Nucleus. Note=Mainly nuclear. Binds to chromatin. Localizes to the cytoplasm when monoubiquitinated by the E2/E3 hybrid ubiquitin-protein ligase UBE2O (PubMed:24703950). {ECO:0000269|PubMed:24703950}.
Tissue Specificity Highly expressed in testis, placenta and ovary. Expressed in breast. {ECO:0000269|PubMed:9528852}.

Rabbit anti-BAP1 Antibody, Affinity Purified - PLA0248 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunofluorescence</B>: This antibody is qualified for the Proximity Ligation Assay (PLA). The above image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red).

Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), Human, ELISA Kit - E01U0035 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Ubiquitin carboxyl terminal hydrolase BAP1 (BAP1), ELISA Kit - MBS7246297 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/mL.

Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), ELISA Kit - MBS7240465 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), ELISA Kit - MBS7219495 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), ELISA Kit - MBS7240258 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), ELISA Kit - MBS7248218 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), ELISA Kit - MBS7205475 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), ELISA Kit - MBS7242108 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), ELISA Kit - MBS7214974 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), ELISA Kit - MBS7226563 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), ELISA Kit - MBS7225564 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ubiquitin carboxyl-terminal hydrolase BAP1 (BAP1), ELISA Kit - MBS7203551 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human BAP1 ELISA Kit - E040264 from Biobool

Category ELISA Kit
Sensitivity 1.0 ng/mL.

anti-BAP1 / UCHL2 antibody - ARG56326 from Arigo Biolaboratories

Category ELISA Kit

Bap1 (Ubiquitin carboxyl-terminal hydrolase BAP1), ELISA Kit - MBS7606140 from MyBioSource

Category ELISA Kit
Prices $295.00, $390.00, $1,615.00, $3,015.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.094ng/ml
Range 0.156-10ng/ml
Search more